ANTIGENICITY, IMMUNOGENICITY, AND PROTECTIVE EFFICACY OF PLASMODIUM VIVAX MSP1 PV200L: A POTENTIAL MALARIA VACCINE SUBUNIT

The merozoite surface protein 1 (MSP-1) is expressed in all Plasmodium species and is considered a major malaria vaccine candidate. We found that MSP-1 from Plasmodium vivax (PvMSP-1) contains a region of significant sequence homology with the 190L subunit vaccine derived from the P. falciparum MSP-...

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Veröffentlicht in:	The American journal of tropical medicine and hygiene 2005-11, Vol.73 (5 suppl), p.16-24
Hauptverfasser:	VALDERRAMA-AGUIRRE, AUGUSTO, QUINTERO, GUSTAVO, GOMEZ, ANDRES, CASTELLANOS, ALEJANDRO, PEREZ, YOBANA, MENDEZ, FABIAN, AREVALO-HERRERA, MYRIAM, HERRERA, SOCRATES
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antibodies, Protozoan - blood Antigens, Protozoan - chemistry Antigens, Protozoan - genetics Antigens, Protozoan - immunology Antigens, Protozoan - metabolism Antigens, Surface - chemistry Antigens, Surface - genetics Antigens, Surface - immunology Antigens, Surface - metabolism Aotus Cebidae Colombia - epidemiology Cross-Sectional Studies Escherichia coli Escherichia coli - genetics Escherichia coli - metabolism Humans Immunization Immunoglobulin G - blood Malaria Vaccines - administration & dosage Malaria Vaccines - genetics Malaria Vaccines - immunology Malaria, Vivax - epidemiology Malaria, Vivax - immunology Malaria, Vivax - prevention & control Merozoite Surface Protein 1 - chemistry Mice Mice, Inbred BALB C Molecular Sequence Data Plasmodium Plasmodium falciparum Plasmodium vivax Plasmodium vivax - immunology Plasmodium vivax - pathogenicity Recombinant Proteins - genetics Recombinant Proteins - immunology Recombinant Proteins - metabolism Seroepidemiologic Studies
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