Regulation of nuclear factor-kappaB (NF-kappaB) activity and apoptosis by estradiol in bovine granulosa cells

Although atresia of bovine follicles is associated with apoptosis of granulosa cells, the signals initiating this cell death have not been resolved. NF-kappaB has been implicated as an important regulator of genes controlling apoptosis, and previous studies indicate that estradiol may modulate NF-ka...

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Veröffentlicht in:Molecular and cellular endocrinology 2005-11, Vol.243 (1-2), p.66-73
Hauptverfasser: Valdez, Kelli E, Turzillo, Adele M
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Sprache:eng
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