Hypothalamic ghrelin treatment modulates NPY-but not CRH-ergic activity in adrenalectomized rats subjected to food restriction: Evidence of a novel hypothalamic ghrelin effect

It has been proposed that ghrelin induces food intake by a mechanism due to the stimulation of hypothalamic NPY-ergic activity. It is recognized that bilateral adrenalectomy (ADX) enhances hypothalamic CRH-ergic function and reduces appetite. Thus, the aim of the present study was to test whether, i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Endocrine 2006-06, Vol.29 (3), p.477-484
Hauptverfasser:	Spinedi, Eduardo, Voirol, Marie-Jeanne, Verdumo, Chantal, Giacominni, Marco, Pralong, François, Gaillard, Rolf C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenalectomy Adrenocorticotropic Hormone - blood Animals Body Weight Corticotropin-Releasing Hormone - metabolism Drug Administration Routes Eating - drug effects Food Deprivation - physiology Gene Expression - drug effects Ghrelin Glucocorticoids - physiology Hypothalamus - drug effects Hypothalamus - metabolism Injections - methods Leptin - blood Male Neuropeptide Y - metabolism Peptide Hormones - administration & dosage Peptide Hormones - blood Peptide Hormones - pharmacology Rats Rats, Wistar RNA, Messenger - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!