Early changes in the skin microcirculation and muscle metabolism of the diabetic foot

Changes in the large vessels and microcirculation of the diabetic foot are important in the development of foot ulceration and subsequent failure to heal existing ulcers. We investigated whether oxygen delivery and muscle metabolism of the lower extremity were factors in diabetic foot disease. We st...

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Veröffentlicht in:	The Lancet (British edition) 2005-11, Vol.366 (9498), p.1711-1717
Hauptverfasser:	Greenman, Robert L, Panasyuk, Svetlana, Wang, Xiaoen, Lyons, Thomas E, Dinh, Thanh, Longoria, Lydia, Giurini, John M, Freeman, Jenny, Khaodhiar, Lalita, Veves, Aristidis
Format:	Artikel
Sprache:	eng
Schlagworte:	Associated diseases and complications Biological and medical sciences Blood vessels Case-Control Studies Diabetes Diabetes Mellitus - metabolism Diabetes. Impaired glucose tolerance Diabetic Foot - metabolism Diabetic Neuropathies - metabolism Endocrine pancreas. Apud cells (diseases) Endocrinopathies Energy reserves Etiopathogenesis. Screening. Investigations. Target tissue resistance Feet Female Forearm General aspects Humans Male Medical imaging Medical sciences Metabolism Microcirculation Middle Aged Muscle, Skeletal - metabolism Muscles Muscular system Oxygen - metabolism Skin - blood supply
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