Chronic Resistance Exercise Training Improves Natural Killer Cell Activity in Older Women

Chronic Resistance Exercise Training Improves Natural Killer Cell Activity in Older Women

Background. Regular exercise has been reported to slow the age-associated declines in natural killer cell activity (NKCA). To evaluate this response, we recruited older, postmenopausal women (65–85 years old) to fill one of two groups: training (10 weeks of resistance exercise; TR) or control. Metho...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2005-10, Vol.60 (10), p.1315-1318
Hauptverfasser: McFarlin, Brian K., Flynn, Michael G., Phillips, Melody D., Stewart, Laura K., Timmerman, Kyle L.
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Exercise
Exercise - physiology
Female
Flow Cytometry
Humans
Immune system
Killer Cells, Natural - physiology
Leukocyte Count
Older people
Risk factors
Women
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Background. Regular exercise has been reported to slow the age-associated declines in natural killer cell activity (NKCA). To evaluate this response, we recruited older, postmenopausal women (65–85 years old) to fill one of two groups: training (10 weeks of resistance exercise; TR) or control. Methods. Blood samples were collected from an arm vein in the TR group at rest (PRE), immediately following (POST), and 2 hours (2H) following an acute bout of resistance exercise both before (BEFORE) and after (AFTER) training. Leukocytes and NKCA were determined by flow cytometry and a whole blood 51Cr release assay, respectively. Results. Acute exercise increased total leukocyte (p
ISSN:1079-5006
1758-535X
DOI:10.1093/gerona/60.10.1315