Molecular Orientation of Porphyrins Accompanying the Formation of Chain-Aligned DNA Films
Porphyrin-containing DNA solid films with several binding orientations were successfully prepared by drying the aqueous solution of porphyrins and DNA in a magnetic field. By the measurement of linear dichroism absorption spectra from three identical spatial directions, the molecular orientations of...
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| Veröffentlicht in: | Biomacromolecules 2005-11, Vol.6 (6), p.3259-3266 |
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| creator | Morii, Nahoko Kido, Giyuu Konakahara, Takeo Morii, Hisayuki |
| description | Porphyrin-containing DNA solid films with several binding orientations were successfully prepared by drying the aqueous solution of porphyrins and DNA in a magnetic field. By the measurement of linear dichroism absorption spectra from three identical spatial directions, the molecular orientations of porphyrins in chain-aligned DNA films were evaluated. Tetra(N-methylpyridinium-4-yl)-porphyrin was found to be bound at the surface of DNA chains like a patch. This orientation is different from the intercalative or groove binding manners observed in solutions. In contrast, tetra(4-sulfonatophenyl)-porphyrin exhibited an orientation perpendicular to the DNA axis, which may be attributed to H-aggregation of porphyrins along the direction parallel to DNA chains. Heme-protein with coiled coil backbone was also aligned along the DNA chains, orienting ferric protoporphyrin parallel to the magnetic field. The major effect for these molecular orientations would be the molecular packing of the rod−disk or the rod−rod systems. |
| doi_str_mv | 10.1021/bm050302z |
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By the measurement of linear dichroism absorption spectra from three identical spatial directions, the molecular orientations of porphyrins in chain-aligned DNA films were evaluated. Tetra(N-methylpyridinium-4-yl)-porphyrin was found to be bound at the surface of DNA chains like a patch. This orientation is different from the intercalative or groove binding manners observed in solutions. In contrast, tetra(4-sulfonatophenyl)-porphyrin exhibited an orientation perpendicular to the DNA axis, which may be attributed to H-aggregation of porphyrins along the direction parallel to DNA chains. Heme-protein with coiled coil backbone was also aligned along the DNA chains, orienting ferric protoporphyrin parallel to the magnetic field. The major effect for these molecular orientations would be the molecular packing of the rod−disk or the rod−rod systems.</description><identifier>ISSN: 1525-7797</identifier><identifier>EISSN: 1526-4602</identifier><identifier>DOI: 10.1021/bm050302z</identifier><identifier>PMID: 16283754</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Animals ; Applied sciences ; Biocompatible Materials - chemistry ; Cations ; Circular Dichroism ; DNA - chemistry ; Exact sciences and technology ; Heme - chemistry ; Intercalating Agents - pharmacology ; Iron - chemistry ; Ligands ; Macromolecular Substances - chemistry ; Magnetics ; Male ; Miscellaneous ; Models, Chemical ; Models, Molecular ; Models, Statistical ; Molecular Conformation ; Natural polymers ; Physicochemistry of polymers ; Porphyrins - chemistry ; Protein Binding ; Protoporphyrins - chemistry ; Salmon ; Spectrophotometry ; Spectrophotometry, Ultraviolet ; Spectrum Analysis ; Spermatozoa ; Ultraviolet Rays</subject><ispartof>Biomacromolecules, 2005-11, Vol.6 (6), p.3259-3266</ispartof><rights>Copyright © 2005 American Chemical Society</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a374t-c9d866ac4e477cb9068caeb50bdfc8b70c736d1d0d864e13d1d6a192847e49223</citedby><cites>FETCH-LOGICAL-a374t-c9d866ac4e477cb9068caeb50bdfc8b70c736d1d0d864e13d1d6a192847e49223</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/bm050302z$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/bm050302z$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,776,780,2751,27055,27903,27904,56716,56766</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17280983$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16283754$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Morii, Nahoko</creatorcontrib><creatorcontrib>Kido, Giyuu</creatorcontrib><creatorcontrib>Konakahara, Takeo</creatorcontrib><creatorcontrib>Morii, Hisayuki</creatorcontrib><title>Molecular Orientation of Porphyrins Accompanying the Formation of Chain-Aligned DNA Films</title><title>Biomacromolecules</title><addtitle>Biomacromolecules</addtitle><description>Porphyrin-containing DNA solid films with several binding orientations were successfully prepared by drying the aqueous solution of porphyrins and DNA in a magnetic field. By the measurement of linear dichroism absorption spectra from three identical spatial directions, the molecular orientations of porphyrins in chain-aligned DNA films were evaluated. Tetra(N-methylpyridinium-4-yl)-porphyrin was found to be bound at the surface of DNA chains like a patch. This orientation is different from the intercalative or groove binding manners observed in solutions. In contrast, tetra(4-sulfonatophenyl)-porphyrin exhibited an orientation perpendicular to the DNA axis, which may be attributed to H-aggregation of porphyrins along the direction parallel to DNA chains. Heme-protein with coiled coil backbone was also aligned along the DNA chains, orienting ferric protoporphyrin parallel to the magnetic field. The major effect for these molecular orientations would be the molecular packing of the rod−disk or the rod−rod systems.</description><subject>Animals</subject><subject>Applied sciences</subject><subject>Biocompatible Materials - chemistry</subject><subject>Cations</subject><subject>Circular Dichroism</subject><subject>DNA - chemistry</subject><subject>Exact sciences and technology</subject><subject>Heme - chemistry</subject><subject>Intercalating Agents - pharmacology</subject><subject>Iron - chemistry</subject><subject>Ligands</subject><subject>Macromolecular Substances - chemistry</subject><subject>Magnetics</subject><subject>Male</subject><subject>Miscellaneous</subject><subject>Models, Chemical</subject><subject>Models, Molecular</subject><subject>Models, Statistical</subject><subject>Molecular Conformation</subject><subject>Natural polymers</subject><subject>Physicochemistry of polymers</subject><subject>Porphyrins - chemistry</subject><subject>Protein Binding</subject><subject>Protoporphyrins - chemistry</subject><subject>Salmon</subject><subject>Spectrophotometry</subject><subject>Spectrophotometry, Ultraviolet</subject><subject>Spectrum Analysis</subject><subject>Spermatozoa</subject><subject>Ultraviolet Rays</subject><issn>1525-7797</issn><issn>1526-4602</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0DtPwzAUBWALgSivgT-AsoDEELh-J2NVKCDxGmBgihzHaY0Su9jJUH49gVZ0QWK6Z_h0rnQQOsZwgYHgy7IFDhTI5xbaw5yIlAkg2z-Zp1LmcoT2Y3wHgJwyvotGWJCMSs720NuDb4zuGxWSp2CN61RnvUt8nTz7sJgvg3UxGWvt24VyS-tmSTc3ydSH9hdO5sq6dNzYmTNVcvU4Tqa2aeMh2qlVE83R-h6g1-n1y-Q2vX-6uZuM71NFJetSnVeZEEozw6TUZQ4i08qUHMqq1lkpQUsqKlzBwJjBdIhC4ZxkTBqWE0IP0NmqdxH8R29iV7Q2atM0yhnfx0JkMueUwL-QABeSUj7A8xXUwccYTF0sgm1VWBYYiu_Bi9_BB3uyLu3L1lQbuV54AKdroKJWTR2U0zZunCQZ5BndOKVj8e774IbR_nj4Bfvgk6A</recordid><startdate>20051101</startdate><enddate>20051101</enddate><creator>Morii, Nahoko</creator><creator>Kido, Giyuu</creator><creator>Konakahara, Takeo</creator><creator>Morii, Hisayuki</creator><general>American Chemical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7TM</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20051101</creationdate><title>Molecular Orientation of Porphyrins Accompanying the Formation of Chain-Aligned DNA Films</title><author>Morii, Nahoko ; Kido, Giyuu ; Konakahara, Takeo ; Morii, Hisayuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a374t-c9d866ac4e477cb9068caeb50bdfc8b70c736d1d0d864e13d1d6a192847e49223</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Animals</topic><topic>Applied sciences</topic><topic>Biocompatible Materials - chemistry</topic><topic>Cations</topic><topic>Circular Dichroism</topic><topic>DNA - chemistry</topic><topic>Exact sciences and technology</topic><topic>Heme - chemistry</topic><topic>Intercalating Agents - pharmacology</topic><topic>Iron - chemistry</topic><topic>Ligands</topic><topic>Macromolecular Substances - chemistry</topic><topic>Magnetics</topic><topic>Male</topic><topic>Miscellaneous</topic><topic>Models, Chemical</topic><topic>Models, Molecular</topic><topic>Models, Statistical</topic><topic>Molecular Conformation</topic><topic>Natural polymers</topic><topic>Physicochemistry of polymers</topic><topic>Porphyrins - chemistry</topic><topic>Protein Binding</topic><topic>Protoporphyrins - chemistry</topic><topic>Salmon</topic><topic>Spectrophotometry</topic><topic>Spectrophotometry, Ultraviolet</topic><topic>Spectrum Analysis</topic><topic>Spermatozoa</topic><topic>Ultraviolet Rays</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Morii, Nahoko</creatorcontrib><creatorcontrib>Kido, Giyuu</creatorcontrib><creatorcontrib>Konakahara, Takeo</creatorcontrib><creatorcontrib>Morii, Hisayuki</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Biomacromolecules</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Morii, Nahoko</au><au>Kido, Giyuu</au><au>Konakahara, Takeo</au><au>Morii, Hisayuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Molecular Orientation of Porphyrins Accompanying the Formation of Chain-Aligned DNA Films</atitle><jtitle>Biomacromolecules</jtitle><addtitle>Biomacromolecules</addtitle><date>2005-11-01</date><risdate>2005</risdate><volume>6</volume><issue>6</issue><spage>3259</spage><epage>3266</epage><pages>3259-3266</pages><issn>1525-7797</issn><eissn>1526-4602</eissn><abstract>Porphyrin-containing DNA solid films with several binding orientations were successfully prepared by drying the aqueous solution of porphyrins and DNA in a magnetic field. By the measurement of linear dichroism absorption spectra from three identical spatial directions, the molecular orientations of porphyrins in chain-aligned DNA films were evaluated. Tetra(N-methylpyridinium-4-yl)-porphyrin was found to be bound at the surface of DNA chains like a patch. This orientation is different from the intercalative or groove binding manners observed in solutions. In contrast, tetra(4-sulfonatophenyl)-porphyrin exhibited an orientation perpendicular to the DNA axis, which may be attributed to H-aggregation of porphyrins along the direction parallel to DNA chains. Heme-protein with coiled coil backbone was also aligned along the DNA chains, orienting ferric protoporphyrin parallel to the magnetic field. The major effect for these molecular orientations would be the molecular packing of the rod−disk or the rod−rod systems.</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><pmid>16283754</pmid><doi>10.1021/bm050302z</doi><tpages>8</tpages></addata></record> |
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| subjects | Animals Applied sciences Biocompatible Materials - chemistry Cations Circular Dichroism DNA - chemistry Exact sciences and technology Heme - chemistry Intercalating Agents - pharmacology Iron - chemistry Ligands Macromolecular Substances - chemistry Magnetics Male Miscellaneous Models, Chemical Models, Molecular Models, Statistical Molecular Conformation Natural polymers Physicochemistry of polymers Porphyrins - chemistry Protein Binding Protoporphyrins - chemistry Salmon Spectrophotometry Spectrophotometry, Ultraviolet Spectrum Analysis Spermatozoa Ultraviolet Rays |
| title | Molecular Orientation of Porphyrins Accompanying the Formation of Chain-Aligned DNA Films |
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