Quantitative Ultrasound in the Evaluation of Bone Status in Premature and Full-Term Infants
Metabolic bone disease of prematurity (MBDP) is a common and significant problem that often gives rise to osteopenia, fractures, osteomalacia, and osteoporosis. The purpose of our study is to establish normative data on bone status in premature and full-term infants to help future studies on MBDP. B...
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Veröffentlicht in: | Journal of clinical densitometry 2006-07, Vol.9 (3), p.358-362 |
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creator | Teitelbaum, Jonathan E. Rodriguez, Ricardo J. Ashmeade, Terri L. Yaniv, Irit Osuntokun, Bankole O. Hudome, Susan Fanaroff, Avory |
description | Metabolic bone disease of prematurity (MBDP) is a common and significant problem that often gives rise to osteopenia, fractures, osteomalacia, and osteoporosis. The purpose of our study is to establish normative data on bone status in premature and full-term infants to help future studies on MBDP. Bone status was prospectively determined as part of a multicenter study among newborns within 96 hours of life. The patients were divided into 2 groups: group 1 included those neonates 25–36 wk gestational age (premature), and group 2 neonates were born at 37–42 wk gestational age (full term). Demographic data were collected. The Omnisense 7000 Bone Sonometer (Sunlight Medical Ltd., Tel-Aviv, Israel) was used to determine the speed of sound (SOS) through the mid tibia, which reflects bone strength. A total of 235 patients were enrolled in this study. Group 1 (i.e., the premature infants) had a statistically lower age-adjusted SOS as compared with group 2 (i.e., the full-term infants) (analysis of variance;
p
=
0.001). There was also a correlation between SOS and birth weight (r
=
0.3;
p
<
001). This study represents the largest database of normative data for bone status measuring in preterm and term infants. |
doi_str_mv | 10.1016/j.jocd.2006.03.013 |
format | Article |
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p
=
0.001). There was also a correlation between SOS and birth weight (r
=
0.3;
p
<
001). This study represents the largest database of normative data for bone status measuring in preterm and term infants.</description><identifier>ISSN: 1094-6950</identifier><identifier>EISSN: 1559-0747</identifier><identifier>DOI: 10.1016/j.jocd.2006.03.013</identifier><identifier>PMID: 16931356</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Bone and Bones - diagnostic imaging ; Bone Density ; Bone Diseases, Metabolic - diagnostic imaging ; bone sonometer ; Female ; Humans ; Infant, Newborn ; Infant, Premature ; Infant, Premature, Diseases - diagnostic imaging ; Male ; metabolic bone disease of prematurity ; osteoporosis ; Osteoporosis - diagnostic imaging ; Prospective Studies ; Reference Values ; speed of sound ; Ultrasonography</subject><ispartof>Journal of clinical densitometry, 2006-07, Vol.9 (3), p.358-362</ispartof><rights>2006 The International Society for Clinical Densitometry</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c403t-2301b0ffe737ea280b90b3131bb82044a9edb9b5fac4e29e69b36c65e298fe5d3</citedby><cites>FETCH-LOGICAL-c403t-2301b0ffe737ea280b90b3131bb82044a9edb9b5fac4e29e69b36c65e298fe5d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jocd.2006.03.013$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16931356$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Teitelbaum, Jonathan E.</creatorcontrib><creatorcontrib>Rodriguez, Ricardo J.</creatorcontrib><creatorcontrib>Ashmeade, Terri L.</creatorcontrib><creatorcontrib>Yaniv, Irit</creatorcontrib><creatorcontrib>Osuntokun, Bankole O.</creatorcontrib><creatorcontrib>Hudome, Susan</creatorcontrib><creatorcontrib>Fanaroff, Avory</creatorcontrib><title>Quantitative Ultrasound in the Evaluation of Bone Status in Premature and Full-Term Infants</title><title>Journal of clinical densitometry</title><addtitle>J Clin Densitom</addtitle><description>Metabolic bone disease of prematurity (MBDP) is a common and significant problem that often gives rise to osteopenia, fractures, osteomalacia, and osteoporosis. The purpose of our study is to establish normative data on bone status in premature and full-term infants to help future studies on MBDP. Bone status was prospectively determined as part of a multicenter study among newborns within 96 hours of life. The patients were divided into 2 groups: group 1 included those neonates 25–36 wk gestational age (premature), and group 2 neonates were born at 37–42 wk gestational age (full term). Demographic data were collected. The Omnisense 7000 Bone Sonometer (Sunlight Medical Ltd., Tel-Aviv, Israel) was used to determine the speed of sound (SOS) through the mid tibia, which reflects bone strength. A total of 235 patients were enrolled in this study. Group 1 (i.e., the premature infants) had a statistically lower age-adjusted SOS as compared with group 2 (i.e., the full-term infants) (analysis of variance;
p
=
0.001). There was also a correlation between SOS and birth weight (r
=
0.3;
p
<
001). This study represents the largest database of normative data for bone status measuring in preterm and term infants.</description><subject>Bone and Bones - diagnostic imaging</subject><subject>Bone Density</subject><subject>Bone Diseases, Metabolic - diagnostic imaging</subject><subject>bone sonometer</subject><subject>Female</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infant, Premature</subject><subject>Infant, Premature, Diseases - diagnostic imaging</subject><subject>Male</subject><subject>metabolic bone disease of prematurity</subject><subject>osteoporosis</subject><subject>Osteoporosis - diagnostic imaging</subject><subject>Prospective Studies</subject><subject>Reference Values</subject><subject>speed of sound</subject><subject>Ultrasonography</subject><issn>1094-6950</issn><issn>1559-0747</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1KxDAYRYMo_r-AC8nKXeuXpk0bcKPiHwgq6spFSNKvmKFtNGkHfHszzIA7V7mQcy_JIeSEQc6AifNFvvC2zQsAkQPPgfEtss-qSmZQl_V2yiDLTMgK9shBjAuAgrGm3iV7TEjOeCX2ycfLrMfJTXpyS6Tv_RR09PPYUjfS6RPpzVL3c7r0I_UdvfIj0tcEz3EFPAccUg5IdWrczn2fvWEY6MPYpdF4RHY63Uc83pyH5P325u36Pnt8unu4vnzMbAl8ygoOzEDXYc1r1EUDRoJJz2PGNAWUpZbYGmmqTtsSC4lCGi6sqFJuOqxafkjO1rtfwX_PGCc1uGix7_WIfo5KNLXksioTWKxBG3yMATv1Fdygw49ioFZK1UKtlKqVUgVcJaWpdLpZn82A7V9l4zABF2sA0x-XDoOK1uFosXUB7aRa7_7b_wUl7IhB</recordid><startdate>20060701</startdate><enddate>20060701</enddate><creator>Teitelbaum, Jonathan E.</creator><creator>Rodriguez, Ricardo J.</creator><creator>Ashmeade, Terri L.</creator><creator>Yaniv, Irit</creator><creator>Osuntokun, Bankole O.</creator><creator>Hudome, Susan</creator><creator>Fanaroff, Avory</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20060701</creationdate><title>Quantitative Ultrasound in the Evaluation of Bone Status in Premature and Full-Term Infants</title><author>Teitelbaum, Jonathan E. ; Rodriguez, Ricardo J. ; Ashmeade, Terri L. ; Yaniv, Irit ; Osuntokun, Bankole O. ; Hudome, Susan ; Fanaroff, Avory</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c403t-2301b0ffe737ea280b90b3131bb82044a9edb9b5fac4e29e69b36c65e298fe5d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Bone and Bones - diagnostic imaging</topic><topic>Bone Density</topic><topic>Bone Diseases, Metabolic - diagnostic imaging</topic><topic>bone sonometer</topic><topic>Female</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Infant, Premature</topic><topic>Infant, Premature, Diseases - diagnostic imaging</topic><topic>Male</topic><topic>metabolic bone disease of prematurity</topic><topic>osteoporosis</topic><topic>Osteoporosis - diagnostic imaging</topic><topic>Prospective Studies</topic><topic>Reference Values</topic><topic>speed of sound</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Teitelbaum, Jonathan E.</creatorcontrib><creatorcontrib>Rodriguez, Ricardo J.</creatorcontrib><creatorcontrib>Ashmeade, Terri L.</creatorcontrib><creatorcontrib>Yaniv, Irit</creatorcontrib><creatorcontrib>Osuntokun, Bankole O.</creatorcontrib><creatorcontrib>Hudome, Susan</creatorcontrib><creatorcontrib>Fanaroff, Avory</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical densitometry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Teitelbaum, Jonathan E.</au><au>Rodriguez, Ricardo J.</au><au>Ashmeade, Terri L.</au><au>Yaniv, Irit</au><au>Osuntokun, Bankole O.</au><au>Hudome, Susan</au><au>Fanaroff, Avory</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quantitative Ultrasound in the Evaluation of Bone Status in Premature and Full-Term Infants</atitle><jtitle>Journal of clinical densitometry</jtitle><addtitle>J Clin Densitom</addtitle><date>2006-07-01</date><risdate>2006</risdate><volume>9</volume><issue>3</issue><spage>358</spage><epage>362</epage><pages>358-362</pages><issn>1094-6950</issn><eissn>1559-0747</eissn><abstract>Metabolic bone disease of prematurity (MBDP) is a common and significant problem that often gives rise to osteopenia, fractures, osteomalacia, and osteoporosis. The purpose of our study is to establish normative data on bone status in premature and full-term infants to help future studies on MBDP. Bone status was prospectively determined as part of a multicenter study among newborns within 96 hours of life. The patients were divided into 2 groups: group 1 included those neonates 25–36 wk gestational age (premature), and group 2 neonates were born at 37–42 wk gestational age (full term). Demographic data were collected. The Omnisense 7000 Bone Sonometer (Sunlight Medical Ltd., Tel-Aviv, Israel) was used to determine the speed of sound (SOS) through the mid tibia, which reflects bone strength. A total of 235 patients were enrolled in this study. Group 1 (i.e., the premature infants) had a statistically lower age-adjusted SOS as compared with group 2 (i.e., the full-term infants) (analysis of variance;
p
=
0.001). There was also a correlation between SOS and birth weight (r
=
0.3;
p
<
001). This study represents the largest database of normative data for bone status measuring in preterm and term infants.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>16931356</pmid><doi>10.1016/j.jocd.2006.03.013</doi><tpages>5</tpages></addata></record> |
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subjects | Bone and Bones - diagnostic imaging Bone Density Bone Diseases, Metabolic - diagnostic imaging bone sonometer Female Humans Infant, Newborn Infant, Premature Infant, Premature, Diseases - diagnostic imaging Male metabolic bone disease of prematurity osteoporosis Osteoporosis - diagnostic imaging Prospective Studies Reference Values speed of sound Ultrasonography |
title | Quantitative Ultrasound in the Evaluation of Bone Status in Premature and Full-Term Infants |
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