Leptin as a Proinflammatory Cytokine

Leptin is a 16-kDa protein produced mainly by adipocytes. Animal models demonstrate that leptin is required for control of bodyweight and reproduction, since mice defective in leptin or the leptin receptor are obese, hyperphagic insulin resistant and infertile. Our initial series of observations lea...

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Veröffentlicht in:Contributions to nephrology 2006-01, Vol.151, p.151-164
1. Verfasser: Lord, Graham M.
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Sprache:eng
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