Diffuse optical measurement of blood flow in breast tumors

Blood flow contrast between tumor and normal tissues in patients with malignant and benign breast cancer was measured by diffuse optical correlation methods. The measurements were carried out with a hand-held optical probe that was manually scanned over the tumor-bearing breast. Increased blood flow...

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Veröffentlicht in:Optics letters 2005-11, Vol.30 (21), p.2915-2917
Hauptverfasser: DURDURAN, Turgut, CHOE, Regine, GUOQIANG YU, CHAO ZHOU, TCHOU, Julia C, CZERNIECKI, Brian J, YODH, Arjun G
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container_end_page 2917
container_issue 21
container_start_page 2915
container_title Optics letters
container_volume 30
creator DURDURAN, Turgut
CHOE, Regine
GUOQIANG YU
CHAO ZHOU
TCHOU, Julia C
CZERNIECKI, Brian J
YODH, Arjun G
description Blood flow contrast between tumor and normal tissues in patients with malignant and benign breast cancer was measured by diffuse optical correlation methods. The measurements were carried out with a hand-held optical probe that was manually scanned over the tumor-bearing breast. Increased blood flow was observed in tumor regions relative to healthy tissue, and control subjects did not exhibit significant blood flow heterogeneity. The measurements introduce a new optical contrast for diffuse optical mammography.
doi_str_mv 10.1364/OL.30.002915
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source MEDLINE; Optica Publishing Group Journals
subjects Biological and medical sciences
Blood Flow Velocity
Breast Neoplasms - blood supply
Breast Neoplasms - pathology
Equipment Design
Equipment Failure Analysis
Exact sciences and technology
Fundamental and applied biological sciences. Psychology
Fundamental areas of phenomenology (including applications)
General aspects, investigation technics, apparatus
Humans
Image Interpretation, Computer-Assisted - methods
Image reconstruction
tomography
Imaging and optical processing
Medical imaging: general
Neovascularization, Pathologic - pathology
Optics
Physics
Spectrophotometry, Infrared - instrumentation
Spectrophotometry, Infrared - methods
Tissues, organs and organisms biophysics
Tomography, Optical - instrumentation
Tomography, Optical - methods
title Diffuse optical measurement of blood flow in breast tumors
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