Downregulation of the RECK-tumor and metastasis suppressor gene in glioma invasiveness

Invasive behavior is the pathological hallmark of malignant gliomas, being responsible for the failure of surgery, radiation, and chemotherapy. Matrix metalloproteinases (MMPs) are essential for proper ECM remodeling and invasion. The tumor and metastasis suppressor RECK protein regulates at least t...

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Veröffentlicht in:	Journal of cellular biochemistry 2006-09, Vol.99 (1), p.156-167
Hauptverfasser:	Corrẽa, Tatiana C. Silveira, Brohem, Carla Abdo, Winnischofer, Sheila Maria Brochado, da Silva Cardeal, Laura Beatriz, Sasahara, Regina Maki, Taboga, Sebastião Roberto, Sogayar, Mari Cleide, Maria-Engler, Silvya Stuchi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line, Tumor Cell Proliferation Central Nervous System Neoplasms - genetics Central Nervous System Neoplasms - pathology collagen Down-Regulation Gene Expression Regulation, Neoplastic Genes, Tumor Suppressor glioma Glioma - genetics Glioma - pathology GPI-Linked Proteins Humans Matrix Metalloproteinase 2 - genetics Matrix Metalloproteinase 9 - genetics Matrix Metalloproteinases - genetics Matrix Metalloproteinases, Membrane-Associated Membrane Glycoproteins - genetics Microscopy, Electron, Transmission MMPs Neoplasm Invasiveness RECK Tissue Inhibitor of Metalloproteinase-2 - genetics
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