LHRH-conjugated magnetic iron oxide nanoparticles for detection of breast cancer metastases

Targeted delivery of superparamagnetic iron oxide nanoparticles (SPIONs) could facilitate their accumulation in metastatic cancer cells in peripheral tissues, lymph nodes and bones and enhance the sensitivity of magnetic resonance imaging (MRI). The specificities of luteinizing hormone releasing hor...

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Veröffentlicht in:	Breast cancer research and treatment 2006-09, Vol.99 (2), p.163-176
Hauptverfasser:	LEUSCHNER, Carola, KUMAR, Challa S. S. R, HANSEL, William, SOBOYEJO, Wole, JIKOU ZHOU, HORMES, Josef
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Breast cancer Breast Neoplasms - metabolism Breast Neoplasms - pathology Cancer research Cancer therapies Carrier Proteins - metabolism CHO Cells - metabolism Chorionic Gonadotropin, beta Subunit, Human - pharmacology Contrast Media Cricetinae Cricetulus Disease Models, Animal Female Ferrosoferric Oxide - metabolism Gonadotropin-Releasing Hormone - metabolism Gynecology. Andrology. Obstetrics Hormones Humans Iron Lung Neoplasms - metabolism Lung Neoplasms - secondary Lymph Nodes - metabolism Lymph Nodes - pathology Lymphatic Metastasis - diagnosis Macrophages - metabolism Magnetic Resonance Imaging Male Mammary gland diseases Medical research Medical sciences Mice Mice, Nude Nanoparticles NMR Nuclear magnetic resonance Receptors, LHRH - metabolism Sensitivity and Specificity Sertoli Cells - metabolism Tissue Distribution Tumor Cells, Cultured Tumors
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