Fast Cancer Uptake of 99mTc-labelled Bombesin (99mTc BN1)

In human blood, breakdown of gastrin-releasing peptide and other bombesin-related peptides occurs in less than 15 min. This quick enzymatic cleavage might impair the diagnostic use of labelled bombesin (BN). 99m Tc-labelled bombesin ( 99m Tc BN1) was injected intravenously and dynamic uptake data we...

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Veröffentlicht in:	In vivo (Athens) 2005-11, Vol.19 (6), p.1071-1076
Hauptverfasser:	Scopinaro, F, Di Santo, G P, Tofani, A, Massari, R, Trotta, C, Ragone, M, Archimandritis, S, Varvarigou, A D
Format:	Artikel
Sprache:	eng
Schlagworte:	Bombesin - analogs & derivatives Breast Neoplasms - blood supply Breast Neoplasms - diagnostic imaging Breast Neoplasms - metabolism Carcinoma, Small Cell - blood supply Carcinoma, Small Cell - diagnostic imaging Carcinoma, Small Cell - metabolism Colonic Neoplasms - blood supply Colonic Neoplasms - diagnostic imaging Colonic Neoplasms - metabolism Female Gastrinoma - blood supply Gastrinoma - diagnostic imaging Gastrinoma - metabolism Humans Kinetics Lung Neoplasms - blood supply Lung Neoplasms - diagnostic imaging Lung Neoplasms - metabolism Male Neoplasm Staging Neoplasms - blood supply Neoplasms - diagnostic imaging Neoplasms - metabolism Organotechnetium Compounds Pancreatic Neoplasms - blood supply Pancreatic Neoplasms - diagnostic imaging Pancreatic Neoplasms - metabolism Prostatic Neoplasms - blood supply Prostatic Neoplasms - diagnostic imaging Prostatic Neoplasms - metabolism Radionuclide Imaging Radiopharmaceuticals Receptors, Bombesin - metabolism Rectal Neoplasms - blood supply Rectal Neoplasms - diagnostic imaging Rectal Neoplasms - metabolism Regional Blood Flow
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