A Simple and Fast Method for the Simultaneous Detection of Nine Fibroblast Growth Factor Receptor 3 Mutations in Bladder Cancer and Voided Urine

Purpose: Mutations in the fibroblast growth factor receptor 3 ( FGFR3 ) occur in 50% of primary bladder tumors. An FGFR3 mutation is associated with good prognosis, illustrated by significantly lower percentage of patients with progression and disease-specific mortality. FGFR3 mutations are especial...

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Veröffentlicht in:	Clinical cancer research 2005-11, Vol.11 (21), p.7743-7748
Hauptverfasser:	VAN OERS, Johanna M. M, LURKIN, Irene, VAN EXSEL, Antonius J. A, NIJSEN, Yvette, VAN RHIJN, Bas W. G, VAN DER AA, Madelon N. M, ZWARTHOFF, Ellen C
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences bladder cancer Deoxyribonucleotides - genetics DNA - metabolism DNA Mutational Analysis DNA Primers - genetics Electrophoresis, Capillary FGFR3 Humans Medical sciences Mutation mutation analysis Nephrology. Urinary tract diseases Pharmacology. Drug treatments Polymerase Chain Reaction Polymorphism, Single-Stranded Conformational Prognosis Receptor, Fibroblast Growth Factor, Type 3 - genetics Sensitivity and Specificity Sequence Analysis, DNA Tumors of the urinary system Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - urine Urinary system involvement in other diseases. Miscellaneous Urinary tract. Prostate gland urine
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