Methacrylate-based chromatographic media
This review summarizes the preparation and application of chromatographic separation media based on methacrylate monomers with a major focus on highly crosslinked macroporous beads prepared from 2‐hydroxyethyl methacrylate and glycidyl methacrylate, respectively. The effects of process variables suc...
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| Veröffentlicht in: | Journal of separation science 2005-10, Vol.28 (15), p.1855-1875 |
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| container_end_page | 1875 |
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| container_issue | 15 |
| container_start_page | 1855 |
| container_title | Journal of separation science |
| container_volume | 28 |
| creator | Benes̆, Milan J. Horák, Daniel Svec, Frantisek |
| description | This review summarizes the preparation and application of chromatographic separation media based on methacrylate monomers with a major focus on highly crosslinked macroporous beads prepared from 2‐hydroxyethyl methacrylate and glycidyl methacrylate, respectively. The effects of process variables such as composition of the polymerization mixture that includes monomers, porogenic solvents, and free radical initiator, suspension stabilizer, reaction temperature, and stirring are detailed for both classical and templated suspension polymerization. In addition, specific features of the preparation of monodisperse beads are also discussed. The performance of methacrylate‐based separation media is demonstrated on numerous separations in a variety of chromatographic modes. |
| doi_str_mv | 10.1002/jssc.200500186 |
| format | Article |
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The effects of process variables such as composition of the polymerization mixture that includes monomers, porogenic solvents, and free radical initiator, suspension stabilizer, reaction temperature, and stirring are detailed for both classical and templated suspension polymerization. In addition, specific features of the preparation of monodisperse beads are also discussed. 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| ispartof | Journal of separation science, 2005-10, Vol.28 (15), p.1855-1875 |
| issn | 1615-9306 1615-9314 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Analytical chemistry Beads Characterization Chemistry Chromatographic methods and physical methods associated with chromatography Chromatography Dispersion Exact sciences and technology HPLC Methacrylates Methylmethacrylates Microscopy, Electron, Scanning Microspheres Monodisperse Other chromatographic methods Packings Particles Polymer Polymerization Separation modes Suspension |
| title | Methacrylate-based chromatographic media |
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