RE: “USE OF A BAYESIAN APPROACH TO DECIDE WHEN TO STOP A THERAPEUTIC TRIAL: THE CASE OF A CHEMOPROPHYLAXIS TRIAL IN HUMAN IMMUNODEFICIENCY VIRUS INFECTION”

As a methodological exercise, Kpozehuoen et al.'s Bayesian simulations are an important contribution in exploring the impact of different priors on reducing the size of a clinical acquired immunodeficiency syndrome trial. To compare the claimed efficiency gained by means of this Bayesian approa...

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Veröffentlicht in:American journal of epidemiology 2005-11, Vol.162 (10), p.1033-1035
Hauptverfasser: van Noord, Paulus A. H., van der Tweel, Ingeborg
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container_title American journal of epidemiology
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creator van Noord, Paulus A. H.
van der Tweel, Ingeborg
description As a methodological exercise, Kpozehuoen et al.'s Bayesian simulations are an important contribution in exploring the impact of different priors on reducing the size of a clinical acquired immunodeficiency syndrome trial. To compare the claimed efficiency gained by means of this Bayesian approach with an alternative method, van Nord et al. performed a sequential statistical analysis using the specifications given in the paper.
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source Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Anti-Infective Agents - therapeutic use
Bayes Theorem
Bayesian analysis
Clinical trials
Clinical Trials, Phase III as Topic - methods
Endpoint Determination - methods
Epidemiology
HIV
HIV Infections - drug therapy
Human immunodeficiency virus
Humans
Randomized Controlled Trials as Topic - methods
Research Design
title RE: “USE OF A BAYESIAN APPROACH TO DECIDE WHEN TO STOP A THERAPEUTIC TRIAL: THE CASE OF A CHEMOPROPHYLAXIS TRIAL IN HUMAN IMMUNODEFICIENCY VIRUS INFECTION”
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