Free-Radical-5-exo-Trig Cyclization of Chiral 3-Silylhepta-1,6-dienes:  Concise Approach to the A−B−C Ring Core of Hexacyclinic Acid

Free-radical-mediated 5-exo-trig cyclization of hepta-1,6-dienes 6a − c incorporating an allylsilane moiety was shown to provide at low temperature exclusively the trans-cis cyclopentanes 7a − c in good yield. In contrast, the same reaction with the alkyl analogue 9a led to the formation of all four...

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Veröffentlicht in:	Journal of organic chemistry 2005-09, Vol.70 (20), p.7985-7995
Hauptverfasser:	James, Philippe, Felpin, François-Xavier, Landais, Yannick, Schenk, Kurt
Format:	Artikel
Sprache:	eng
Schlagworte:	Alicyclic compounds Alicyclic compounds, terpenoids, prostaglandins, steroids Chemistry Exact sciences and technology Organic chemistry Preparations and properties
Online-Zugang:	Volltext
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