Density and sub-cellular distribution of cardiac and neuronal sodium channel isoforms in rat ventricular myocytes

In cardiac ventricular myocytes, Na current is generated mainly by the cardiac Na V1.5 isoform, but the presence of “neuronal” Na channel isoforms in the heart has been demonstrated recently. In this study, we quantified the density and sub-cellular distribution of cardiac and neuronal channel isofo...

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Veröffentlicht in:	Biochemical and biophysical research communications 2006-09, Vol.348 (3), p.1163-1166
Hauptverfasser:	Brette, Fabien, Orchard, Clive H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cardiac Electrophysiology Heart Ventricles - cytology Heart Ventricles - metabolism Ion channels Muscle Proteins - genetics Muscle Proteins - metabolism Myocytes Myocytes, Cardiac - metabolism Protein Isoforms - genetics Protein Isoforms - metabolism Rats Rats, Wistar Sodium Sodium Channels - genetics Sodium Channels - metabolism Subcellular Fractions - metabolism
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