Gq/11‐induced intracellular calcium mobilization mediates Per2 acute induction in Rat‐1 fibroblasts

Phase resetting is one of the essential properties of circadian clocks that is required for the adjustment to a particular environment and the induction of Per1 and Per2 clock genes is believed to be a primary molecular event during this process. Although the intracellular signal transduction pathwa...

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Veröffentlicht in:	Genes to cells : devoted to molecular & cellular mechanisms 2006-09, Vol.11 (9), p.1039-1049
Hauptverfasser:	Takashima, Naoyuki, Fujioka, Atsuko, Hayasaka, Naoto, Matsuo, Ayako, Takasaki, Jun, Shigeyoshi, Yasufumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Butadienes - pharmacology Calcium Signaling - drug effects Egtazic Acid - analogs & derivatives Egtazic Acid - pharmacology Fibroblasts - drug effects Fibroblasts - metabolism GTP-Binding Protein alpha Subunits, Gq-G11 - antagonists & inhibitors GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism Ionomycin - pharmacology Models, Biological Nitriles - pharmacology Nuclear Proteins - genetics Peptides, Cyclic - pharmacology Rats rho GTP-Binding Proteins - antagonists & inhibitors RNA, Messenger - genetics RNA, Messenger - metabolism Thapsigargin - pharmacology Time Factors Transcription Factors - genetics Type C Phospholipases - antagonists & inhibitors Up-Regulation - genetics
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