Piperazine Propanol Derivative as a Novel Antifungal Targeting 1,3-β-D-Glucan Synthase

1,3-β-D-Glucan synthase, which synthesizes a main component of fungal cell wall, is one of the promising targets for antifungal agents. In order to identify novel chemical classes of 1,3-β-D-glucan synthase inhibitors, we screened a chemical library monitoring inhibition of the Candida albicans 1,3-...

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