Insulin Signaling in Adipocytes Differentiated from Mouse Stromal MC3T3-G2/PA6 Cells

The stromal MC3T3-G2/PA6 (PA6) cells from mouse clavaria did not require insulin for differentiation into mature adipose cells, although insulin is well known to play a key role in adipocyte differentiation. Large lipid droplets were observed in the cytoplasm of PA6 cells, and mRNA expression of the...

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Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2005, Vol.28(11), pp.2040-2045
Hauptverfasser:	Morito, Satoshi, Yaguchi, Kuniko, Imada, Mikiko, Tachikawa, Chihiro, Nomura, Masaaki, Moritani, Shuzo, Igarashi, Manabu, Yokogawa, Koichi, Miyamoto, Ken-ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells adipocyte Adipocytes - metabolism Adipocytes - physiology Animals Azo Compounds Coloring Agents Deoxyglucose - metabolism Glucose - metabolism glucose uptake Immunoblotting Insulin - physiology insulin signal Lipolysis MC3T3-G2/PA6 cell Mice Mice, Inbred C57BL Phosphatidylinositol 3-Kinases - metabolism Reverse Transcriptase Polymerase Chain Reaction Signal Transduction - physiology
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