Isolation and absolute configuration of new bioactive marine steroids from Euryspongia n. sp

The apolar fraction of the crude alcoholic extract of the sponge Euryspongia n. sp. was shown to display anti-inflammatory activity. Bioassay guided chromatographic purification led to the isolation of a known compound petrosterol ( 1) of 3β-hydroxy-24-norchol-5-en-23-oic acid ( 2), which has never...

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Veröffentlicht in:	Steroids 2005-12, Vol.70 (13), p.873-878
Hauptverfasser:	Mandeau, Anne, Debitus, Cecile, Ariès, Marie-Françoise, David, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	3β-Hydroxy-26-norcampest-5-en-25-oic acid 6-Ketoprostaglandin F1 alpha - metabolism Absolute configuration Animals Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - isolation & purification Anti-Inflammatory Agents - pharmacology Biological and medical sciences Cell Line Euryspongia n. sp Fundamental and applied biological sciences. Psychology Humans Keratinocytes - cytology Magnetic Resonance Spectroscopy Phenylglycine methyl ester Porifera - chemistry Stereoisomerism Steroids - chemistry Steroids - isolation & purification Steroids - pharmacology Sterols - isolation & purification Vertebrates: endocrinology
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