Perifolliculitis capitis abscedens et suffodiens
ABSTRACT Perifolliculitis capitis abscedens et suffodiens (PCAS) is rare chronic, suppurative and inflammatory scalp disease. Its aetiology and pathogenesis is not completely understood. The treatment is usually difficult and often disappointing. We report a case of 29‐year‐old male who presented wi...
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| Veröffentlicht in: | Journal of the European Academy of Dermatology and Venereology 2005-11, Vol.19 (6), p.719-721 |
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| container_issue | 6 |
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| container_title | Journal of the European Academy of Dermatology and Venereology |
| container_volume | 19 |
| creator | Ljubojevic, S Pasic, A Lipozencic, J Skerlev, M |
| description | ABSTRACT
Perifolliculitis capitis abscedens et suffodiens (PCAS) is rare chronic, suppurative and inflammatory scalp disease. Its aetiology and pathogenesis is not completely understood. The treatment is usually difficult and often disappointing.
We report a case of 29‐year‐old male who presented with tender, fluctuant nodules and abscesses, with draining pus and patchy alopecia on his scalp for 3 years. A skin biopsy from scalp lesions revealed features that are characteristic of perifolliculitis. Initially, the patient was treated with periodic incision and drainage of the scalp abscesses. The answer was very poor. When admitted to our department, isotretinoin was started at daily dose of 30 mg, because initially his cholesterol and triglyceride levels were mildly increased. When dose was reduced to 10 mg the levels of cholesterol and triglyceride remained normal. A response to treatment was excellent and rapid.
The treatment of PCAS represents usually difficulties and frustration for both the patient and the physician. A long course of isotretinoin can be considered as one of the most effective treatment for PCAS. |
| doi_str_mv | 10.1111/j.1468-3083.2005.01215.x |
| format | Article |
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Perifolliculitis capitis abscedens et suffodiens (PCAS) is rare chronic, suppurative and inflammatory scalp disease. Its aetiology and pathogenesis is not completely understood. The treatment is usually difficult and often disappointing.
We report a case of 29‐year‐old male who presented with tender, fluctuant nodules and abscesses, with draining pus and patchy alopecia on his scalp for 3 years. A skin biopsy from scalp lesions revealed features that are characteristic of perifolliculitis. Initially, the patient was treated with periodic incision and drainage of the scalp abscesses. The answer was very poor. When admitted to our department, isotretinoin was started at daily dose of 30 mg, because initially his cholesterol and triglyceride levels were mildly increased. When dose was reduced to 10 mg the levels of cholesterol and triglyceride remained normal. A response to treatment was excellent and rapid.
The treatment of PCAS represents usually difficulties and frustration for both the patient and the physician. A long course of isotretinoin can be considered as one of the most effective treatment for PCAS.</description><identifier>ISSN: 0926-9959</identifier><identifier>EISSN: 1468-3083</identifier><identifier>DOI: 10.1111/j.1468-3083.2005.01215.x</identifier><identifier>PMID: 16268877</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Ltd</publisher><subject>Administration, Topical ; Adult ; Alopecia - etiology ; Folliculitis - drug therapy ; Humans ; isotretinoin ; Keratolytic Agents - administration & dosage ; Keratolytic Agents - therapeutic use ; Male ; perifolliculitis capitis abscedens et suffodiens ; Scalp Dermatoses - drug therapy ; treatment ; Tretinoin - administration & dosage ; Tretinoin - therapeutic use</subject><ispartof>Journal of the European Academy of Dermatology and Venereology, 2005-11, Vol.19 (6), p.719-721</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3675-5b7229a0f6c3831807d2eada51302c5c5c5cd5ce4ebabea0125498c2473c84f73</citedby><cites>FETCH-LOGICAL-c3675-5b7229a0f6c3831807d2eada51302c5c5c5cd5ce4ebabea0125498c2473c84f73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1468-3083.2005.01215.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1468-3083.2005.01215.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16268877$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ljubojevic, S</creatorcontrib><creatorcontrib>Pasic, A</creatorcontrib><creatorcontrib>Lipozencic, J</creatorcontrib><creatorcontrib>Skerlev, M</creatorcontrib><title>Perifolliculitis capitis abscedens et suffodiens</title><title>Journal of the European Academy of Dermatology and Venereology</title><addtitle>J Eur Acad Dermatol Venereol</addtitle><description>ABSTRACT
Perifolliculitis capitis abscedens et suffodiens (PCAS) is rare chronic, suppurative and inflammatory scalp disease. Its aetiology and pathogenesis is not completely understood. The treatment is usually difficult and often disappointing.
We report a case of 29‐year‐old male who presented with tender, fluctuant nodules and abscesses, with draining pus and patchy alopecia on his scalp for 3 years. A skin biopsy from scalp lesions revealed features that are characteristic of perifolliculitis. Initially, the patient was treated with periodic incision and drainage of the scalp abscesses. The answer was very poor. When admitted to our department, isotretinoin was started at daily dose of 30 mg, because initially his cholesterol and triglyceride levels were mildly increased. When dose was reduced to 10 mg the levels of cholesterol and triglyceride remained normal. A response to treatment was excellent and rapid.
The treatment of PCAS represents usually difficulties and frustration for both the patient and the physician. A long course of isotretinoin can be considered as one of the most effective treatment for PCAS.</description><subject>Administration, Topical</subject><subject>Adult</subject><subject>Alopecia - etiology</subject><subject>Folliculitis - drug therapy</subject><subject>Humans</subject><subject>isotretinoin</subject><subject>Keratolytic Agents - administration & dosage</subject><subject>Keratolytic Agents - therapeutic use</subject><subject>Male</subject><subject>perifolliculitis capitis abscedens et suffodiens</subject><subject>Scalp Dermatoses - drug therapy</subject><subject>treatment</subject><subject>Tretinoin - administration & dosage</subject><subject>Tretinoin - therapeutic use</subject><issn>0926-9959</issn><issn>1468-3083</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkEtPwzAMxyMEYmPwFVBP3FqcpHkdOKDx1iQ4ANcoTRMpU7aOZhXbt6fdJrhiH2zLfz_0QyjDUODerucFLrnMKUhaEABWACaYFZsjNP5tHKMxKMJzpZgaobOU5gCAMZOnaIQ54VIKMUbw5trgmxiD7WJYh5RZs9pFUyXrardMmVtnqfO-qUNfnaMTb2JyF4c4QR8P9-_Tp3z2-vg8vZ3llnLBclYJQpQBzy2VFEsQNXGmNgxTIJbtvGbWla4ylTP9_6xU0pJSUCtLL-gEXe33rtrmq3NprRehfyhGs3RNlzSXgnMlyl4o90LbNim1zutVGxam3WoMeqCl53qAogcoeqCld7T0ph-9PNzoqoWr_wYPeHrBzV7wHaLb_nuxfrn7HDL6A3PjeCM</recordid><startdate>200511</startdate><enddate>200511</enddate><creator>Ljubojevic, S</creator><creator>Pasic, A</creator><creator>Lipozencic, J</creator><creator>Skerlev, M</creator><general>Blackwell Science Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200511</creationdate><title>Perifolliculitis capitis abscedens et suffodiens</title><author>Ljubojevic, S ; Pasic, A ; Lipozencic, J ; Skerlev, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3675-5b7229a0f6c3831807d2eada51302c5c5c5cd5ce4ebabea0125498c2473c84f73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Administration, Topical</topic><topic>Adult</topic><topic>Alopecia - etiology</topic><topic>Folliculitis - drug therapy</topic><topic>Humans</topic><topic>isotretinoin</topic><topic>Keratolytic Agents - administration & dosage</topic><topic>Keratolytic Agents - therapeutic use</topic><topic>Male</topic><topic>perifolliculitis capitis abscedens et suffodiens</topic><topic>Scalp Dermatoses - drug therapy</topic><topic>treatment</topic><topic>Tretinoin - administration & dosage</topic><topic>Tretinoin - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ljubojevic, S</creatorcontrib><creatorcontrib>Pasic, A</creatorcontrib><creatorcontrib>Lipozencic, J</creatorcontrib><creatorcontrib>Skerlev, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the European Academy of Dermatology and Venereology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ljubojevic, S</au><au>Pasic, A</au><au>Lipozencic, J</au><au>Skerlev, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Perifolliculitis capitis abscedens et suffodiens</atitle><jtitle>Journal of the European Academy of Dermatology and Venereology</jtitle><addtitle>J Eur Acad Dermatol Venereol</addtitle><date>2005-11</date><risdate>2005</risdate><volume>19</volume><issue>6</issue><spage>719</spage><epage>721</epage><pages>719-721</pages><issn>0926-9959</issn><eissn>1468-3083</eissn><abstract>ABSTRACT
Perifolliculitis capitis abscedens et suffodiens (PCAS) is rare chronic, suppurative and inflammatory scalp disease. Its aetiology and pathogenesis is not completely understood. The treatment is usually difficult and often disappointing.
We report a case of 29‐year‐old male who presented with tender, fluctuant nodules and abscesses, with draining pus and patchy alopecia on his scalp for 3 years. A skin biopsy from scalp lesions revealed features that are characteristic of perifolliculitis. Initially, the patient was treated with periodic incision and drainage of the scalp abscesses. The answer was very poor. When admitted to our department, isotretinoin was started at daily dose of 30 mg, because initially his cholesterol and triglyceride levels were mildly increased. When dose was reduced to 10 mg the levels of cholesterol and triglyceride remained normal. A response to treatment was excellent and rapid.
The treatment of PCAS represents usually difficulties and frustration for both the patient and the physician. A long course of isotretinoin can be considered as one of the most effective treatment for PCAS.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Ltd</pub><pmid>16268877</pmid><doi>10.1111/j.1468-3083.2005.01215.x</doi><tpages>3</tpages></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Administration, Topical Adult Alopecia - etiology Folliculitis - drug therapy Humans isotretinoin Keratolytic Agents - administration & dosage Keratolytic Agents - therapeutic use Male perifolliculitis capitis abscedens et suffodiens Scalp Dermatoses - drug therapy treatment Tretinoin - administration & dosage Tretinoin - therapeutic use |
| title | Perifolliculitis capitis abscedens et suffodiens |
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