Reduced psychostimulant effects on dopamine dynamics in the nucleus accumbens of μ-opioid receptor knockout mice

Dopamine neurotransmission in the nucleus accumbens plays a pivotal role in the reinforcing properties of drugs of abuse. Two interacting processes regulate nucleus accumbens dopamine overflow: release of dopamine from presynaptic terminals and the subsequent reuptake by dopamine transporters. Opioi...

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Veröffentlicht in:	Neuroscience 2006-01, Vol.141 (4), p.1679-1684
Hauptverfasser:	Mathon, D.S., Vanderschuren, L.J.M.J., Ramakers, G.M.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	amphetamine Amphetamine - pharmacology Analysis of Variance Animals Biological and medical sciences Central Nervous System Stimulants - pharmacology cocaine Cocaine - pharmacology Dopamine - metabolism dopamine reuptake Electrochemistry - methods fast scan cyclic voltammetry Fundamental and applied biological sciences. Psychology Medical sciences Mice Mice, Inbred C57BL Mice, Knockout Neuropharmacology nucleus accumbens Nucleus Accumbens - drug effects Pharmacology. Drug treatments Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Receptors, Opioid, mu - deficiency Vertebrates: nervous system and sense organs
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