Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department

The rapid emergence of methicillin-resistant S. aureus (MRSA) as a community pathogen threatens to change the practice of outpatient medicine. In this report, investigators from emergency departments in 11 cities throughout the United States show that S. aureus accounts for 76 percent of culturable...

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Veröffentlicht in:The New England journal of medicine 2006-08, Vol.355 (7), p.666-674
Hauptverfasser: Moran, Gregory J, Krishnadasan, Anusha, Gorwitz, Rachel J, Fosheim, Gregory E, McDougal, Linda K, Carey, Roberta B, Talan, David A
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container_issue 7
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container_title The New England journal of medicine
container_volume 355
creator Moran, Gregory J
Krishnadasan, Anusha
Gorwitz, Rachel J
Fosheim, Gregory E
McDougal, Linda K
Carey, Roberta B
Talan, David A
description The rapid emergence of methicillin-resistant S. aureus (MRSA) as a community pathogen threatens to change the practice of outpatient medicine. In this report, investigators from emergency departments in 11 cities throughout the United States show that S. aureus accounts for 76 percent of culturable skin and soft-tissue infections, of which 59 percent are MRSA. This report shows that S. aureus accounts for 76 percent of culturable skin and soft-tissue infections, of which 59 percent are MRSA. Methicillin-resistant Staphylococcus aureus (MRSA) emerged in the 1960s as a cause of infection among patients exposed to the bacteria in health care settings. 1 More recently, MRSA infections have been reported among persons without such exposure (community-associated MRSA). 2 , 3 Community-associated outbreaks of MRSA infection have occurred among prisoners, intravenous-drug users, athletes, military trainees, and men who have sex with men. 4 – 6 Community-associated MRSA has primarily been described as a cause of skin and soft-tissue infections, but it has also been associated with sepsis and necrotizing pneumonia. 7 – 9 As compared with health care–associated MRSA isolates, community-associated MRSA isolates tend to be resistant . . .
doi_str_mv 10.1056/NEJMoa055356
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subjects Acute Disease
Adult
Aged
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Bacterial Proteins - genetics
Bacterial Toxins - genetics
Biological and medical sciences
Confidence intervals
Departments
Electrophoresis, Gel, Pulsed-Field
Emergency Service, Hospital
Exotoxins - genetics
Female
General aspects
Humans
Leukocidins
Male
Medical sciences
Methicillin Resistance - genetics
Microbial Sensitivity Tests
Middle Aged
Penicillin-Binding Proteins
Soft Tissue Infections - drug therapy
Soft Tissue Infections - microbiology
Staphylococcal Infections - drug therapy
Staphylococcal Infections - microbiology
Staphylococcal Skin Infections - drug therapy
Staphylococcal Skin Infections - microbiology
Staphylococcus aureus
Staphylococcus aureus - drug effects
Staphylococcus aureus - genetics
Staphylococcus infections
United States
title Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department
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