Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department
The rapid emergence of methicillin-resistant S. aureus (MRSA) as a community pathogen threatens to change the practice of outpatient medicine. In this report, investigators from emergency departments in 11 cities throughout the United States show that S. aureus accounts for 76 percent of culturable...
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Veröffentlicht in: | The New England journal of medicine 2006-08, Vol.355 (7), p.666-674 |
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creator | Moran, Gregory J Krishnadasan, Anusha Gorwitz, Rachel J Fosheim, Gregory E McDougal, Linda K Carey, Roberta B Talan, David A |
description | The rapid emergence of methicillin-resistant
S. aureus
(MRSA) as a community pathogen threatens to change the practice of outpatient medicine. In this report, investigators from emergency departments in 11 cities throughout the United States show that
S. aureus
accounts for 76 percent of culturable skin and soft-tissue infections, of which 59 percent are MRSA.
This report shows that
S. aureus
accounts for 76 percent of culturable skin and soft-tissue infections, of which 59 percent are MRSA.
Methicillin-resistant
Staphylococcus aureus
(MRSA) emerged in the 1960s as a cause of infection among patients exposed to the bacteria in health care settings.
1
More recently, MRSA infections have been reported among persons without such exposure (community-associated MRSA).
2
,
3
Community-associated outbreaks of MRSA infection have occurred among prisoners, intravenous-drug users, athletes, military trainees, and men who have sex with men.
4
–
6
Community-associated MRSA has primarily been described as a cause of skin and soft-tissue infections, but it has also been associated with sepsis and necrotizing pneumonia.
7
–
9
As compared with health care–associated MRSA isolates, community-associated MRSA isolates tend to be resistant . . . |
doi_str_mv | 10.1056/NEJMoa055356 |
format | Article |
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S. aureus
(MRSA) as a community pathogen threatens to change the practice of outpatient medicine. In this report, investigators from emergency departments in 11 cities throughout the United States show that
S. aureus
accounts for 76 percent of culturable skin and soft-tissue infections, of which 59 percent are MRSA.
This report shows that
S. aureus
accounts for 76 percent of culturable skin and soft-tissue infections, of which 59 percent are MRSA.
Methicillin-resistant
Staphylococcus aureus
(MRSA) emerged in the 1960s as a cause of infection among patients exposed to the bacteria in health care settings.
1
More recently, MRSA infections have been reported among persons without such exposure (community-associated MRSA).
2
,
3
Community-associated outbreaks of MRSA infection have occurred among prisoners, intravenous-drug users, athletes, military trainees, and men who have sex with men.
4
–
6
Community-associated MRSA has primarily been described as a cause of skin and soft-tissue infections, but it has also been associated with sepsis and necrotizing pneumonia.
7
–
9
As compared with health care–associated MRSA isolates, community-associated MRSA isolates tend to be resistant . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMoa055356</identifier><identifier>PMID: 16914702</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Acute Disease ; Adult ; Aged ; Anti-Bacterial Agents - pharmacology ; Anti-Bacterial Agents - therapeutic use ; Bacterial Proteins - genetics ; Bacterial Toxins - genetics ; Biological and medical sciences ; Confidence intervals ; Departments ; Electrophoresis, Gel, Pulsed-Field ; Emergency Service, Hospital ; Exotoxins - genetics ; Female ; General aspects ; Humans ; Leukocidins ; Male ; Medical sciences ; Methicillin Resistance - genetics ; Microbial Sensitivity Tests ; Middle Aged ; Penicillin-Binding Proteins ; Soft Tissue Infections - drug therapy ; Soft Tissue Infections - microbiology ; Staphylococcal Infections - drug therapy ; Staphylococcal Infections - microbiology ; Staphylococcal Skin Infections - drug therapy ; Staphylococcal Skin Infections - microbiology ; Staphylococcus aureus ; Staphylococcus aureus - drug effects ; Staphylococcus aureus - genetics ; Staphylococcus infections ; United States</subject><ispartof>The New England journal of medicine, 2006-08, Vol.355 (7), p.666-674</ispartof><rights>Copyright © 2006 Massachusetts Medical Society. All rights reserved.</rights><rights>2006 INIST-CNRS</rights><rights>Copyright 2006 Massachusetts Medical Society.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c493t-5a1647fa714e0a534a072b34911a3b86560c71f9a99bf9fcd2511bc99e2ed8d03</citedby><cites>FETCH-LOGICAL-c493t-5a1647fa714e0a534a072b34911a3b86560c71f9a99bf9fcd2511bc99e2ed8d03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMoa055356$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJMoa055356$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18026840$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16914702$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Moran, Gregory J</creatorcontrib><creatorcontrib>Krishnadasan, Anusha</creatorcontrib><creatorcontrib>Gorwitz, Rachel J</creatorcontrib><creatorcontrib>Fosheim, Gregory E</creatorcontrib><creatorcontrib>McDougal, Linda K</creatorcontrib><creatorcontrib>Carey, Roberta B</creatorcontrib><creatorcontrib>Talan, David A</creatorcontrib><creatorcontrib>EMERGEncy ID Net Study Group</creatorcontrib><title>Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>The rapid emergence of methicillin-resistant
S. aureus
(MRSA) as a community pathogen threatens to change the practice of outpatient medicine. In this report, investigators from emergency departments in 11 cities throughout the United States show that
S. aureus
accounts for 76 percent of culturable skin and soft-tissue infections, of which 59 percent are MRSA.
This report shows that
S. aureus
accounts for 76 percent of culturable skin and soft-tissue infections, of which 59 percent are MRSA.
Methicillin-resistant
Staphylococcus aureus
(MRSA) emerged in the 1960s as a cause of infection among patients exposed to the bacteria in health care settings.
1
More recently, MRSA infections have been reported among persons without such exposure (community-associated MRSA).
2
,
3
Community-associated outbreaks of MRSA infection have occurred among prisoners, intravenous-drug users, athletes, military trainees, and men who have sex with men.
4
–
6
Community-associated MRSA has primarily been described as a cause of skin and soft-tissue infections, but it has also been associated with sepsis and necrotizing pneumonia.
7
–
9
As compared with health care–associated MRSA isolates, community-associated MRSA isolates tend to be resistant . . .</description><subject>Acute Disease</subject><subject>Adult</subject><subject>Aged</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Bacterial Proteins - genetics</subject><subject>Bacterial Toxins - genetics</subject><subject>Biological and medical sciences</subject><subject>Confidence intervals</subject><subject>Departments</subject><subject>Electrophoresis, Gel, Pulsed-Field</subject><subject>Emergency Service, Hospital</subject><subject>Exotoxins - genetics</subject><subject>Female</subject><subject>General aspects</subject><subject>Humans</subject><subject>Leukocidins</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Methicillin Resistance - genetics</subject><subject>Microbial Sensitivity Tests</subject><subject>Middle Aged</subject><subject>Penicillin-Binding Proteins</subject><subject>Soft Tissue Infections - drug therapy</subject><subject>Soft Tissue Infections - microbiology</subject><subject>Staphylococcal Infections - drug therapy</subject><subject>Staphylococcal Infections - microbiology</subject><subject>Staphylococcal Skin Infections - drug therapy</subject><subject>Staphylococcal Skin Infections - microbiology</subject><subject>Staphylococcus aureus</subject><subject>Staphylococcus aureus - drug effects</subject><subject>Staphylococcus aureus - genetics</subject><subject>Staphylococcus infections</subject><subject>United States</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqF0U1PFEEQBuAOwciK3jybDkFPDvb3TB8JrooBJSDnSU1vDfRmumfp7jnw7x2ym2CMiXWpQz2pSuUl5C1nJ5xp8-nH8vvlCExrqc0eWXAtZaUUM_tkwZhoKlVbeUBe5bxmc3FlX5IDbixXNRMLcnuJ5d47Pww-VteYfS4QC705oTAlnDI9jz264seYKYQx3tErKB5jydRHWu6RLgOmO4zukX7GDaQS5uFr8qKHIeObXT8kt1-Wv86-VRc_v56fnV5UTllZKg3cqLqHmitkoKUCVotOKss5yK4x2jBX896CtV1ve7cSmvPOWYsCV82KyUPyYbt3k8aHCXNpg88OhwEijlNuTVMbLlT9X8itstYyO8Ojv-B6nFKcn2iFkFYIZZoZfdwil8acE_btJvkA6bHlrH0Kpf0zlJm_2-2cuoCrZ7xLYQbvdwCyg6FPEJ3Pz65hwjTq6d3jrQshtxHX4d_3fgMtAp5e</recordid><startdate>20060817</startdate><enddate>20060817</enddate><creator>Moran, Gregory J</creator><creator>Krishnadasan, Anusha</creator><creator>Gorwitz, Rachel J</creator><creator>Fosheim, Gregory E</creator><creator>McDougal, Linda K</creator><creator>Carey, Roberta B</creator><creator>Talan, David A</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>20060817</creationdate><title>Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department</title><author>Moran, Gregory J ; Krishnadasan, Anusha ; Gorwitz, Rachel J ; Fosheim, Gregory E ; McDougal, Linda K ; Carey, Roberta B ; Talan, David A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c493t-5a1647fa714e0a534a072b34911a3b86560c71f9a99bf9fcd2511bc99e2ed8d03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Acute Disease</topic><topic>Adult</topic><topic>Aged</topic><topic>Anti-Bacterial Agents - 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Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Moran, Gregory J</au><au>Krishnadasan, Anusha</au><au>Gorwitz, Rachel J</au><au>Fosheim, Gregory E</au><au>McDougal, Linda K</au><au>Carey, Roberta B</au><au>Talan, David A</au><aucorp>EMERGEncy ID Net Study Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2006-08-17</date><risdate>2006</risdate><volume>355</volume><issue>7</issue><spage>666</spage><epage>674</epage><pages>666-674</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>The rapid emergence of methicillin-resistant
S. aureus
(MRSA) as a community pathogen threatens to change the practice of outpatient medicine. In this report, investigators from emergency departments in 11 cities throughout the United States show that
S. aureus
accounts for 76 percent of culturable skin and soft-tissue infections, of which 59 percent are MRSA.
This report shows that
S. aureus
accounts for 76 percent of culturable skin and soft-tissue infections, of which 59 percent are MRSA.
Methicillin-resistant
Staphylococcus aureus
(MRSA) emerged in the 1960s as a cause of infection among patients exposed to the bacteria in health care settings.
1
More recently, MRSA infections have been reported among persons without such exposure (community-associated MRSA).
2
,
3
Community-associated outbreaks of MRSA infection have occurred among prisoners, intravenous-drug users, athletes, military trainees, and men who have sex with men.
4
–
6
Community-associated MRSA has primarily been described as a cause of skin and soft-tissue infections, but it has also been associated with sepsis and necrotizing pneumonia.
7
–
9
As compared with health care–associated MRSA isolates, community-associated MRSA isolates tend to be resistant . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><pmid>16914702</pmid><doi>10.1056/NEJMoa055356</doi><tpages>9</tpages></addata></record> |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals; New England Journal of Medicine |
subjects | Acute Disease Adult Aged Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Bacterial Proteins - genetics Bacterial Toxins - genetics Biological and medical sciences Confidence intervals Departments Electrophoresis, Gel, Pulsed-Field Emergency Service, Hospital Exotoxins - genetics Female General aspects Humans Leukocidins Male Medical sciences Methicillin Resistance - genetics Microbial Sensitivity Tests Middle Aged Penicillin-Binding Proteins Soft Tissue Infections - drug therapy Soft Tissue Infections - microbiology Staphylococcal Infections - drug therapy Staphylococcal Infections - microbiology Staphylococcal Skin Infections - drug therapy Staphylococcal Skin Infections - microbiology Staphylococcus aureus Staphylococcus aureus - drug effects Staphylococcus aureus - genetics Staphylococcus infections United States |
title | Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department |
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