High-Resolution X-Ray Microtomography Is a Sensitive Method to Detect Vascular Calcification in Living Rats With Chronic Renal Failure

OBJECTIVE—Chronic renal failure (CRF) is associated with a 10- to 20-fold increase in cardiovascular risk. Vascular calcification is a prominent feature of cardiovascular disease in patients with end-stage renal failure and contributes to the excess mortality in this population. In this study, we ex...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2006-09, Vol.26 (9), p.2110-2116
Hauptverfasser:	Persy, Veerle, Postnov, Andrei, Neven, Ellen, Dams, Geert, De Broe, Marc, DʼHaese, Patrick, De Clerck, Nora
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta, Thoracic - metabolism Aortic Diseases - diagnostic imaging Aortic Diseases - etiology Aortic Diseases - metabolism Aortic Diseases - pathology Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Blood coagulation Calcinosis - diagnostic imaging Calcinosis - etiology Calcinosis - metabolism Calcinosis - pathology Calcium - metabolism Cardiology. Vascular system Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Feasibility Studies Glomerulonephritis Image Processing, Computer-Assisted Imaging, Three-Dimensional In Vitro Techniques Investigative techniques, diagnostic techniques (general aspects) Kidney Failure, Chronic - complications Medical sciences Models, Cardiovascular Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Rats Reproducibility of Results Sensitivity and Specificity Severity of Illness Index Tomography, X-Ray Computed
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