Addressing the fas counterattack controversy : Blocking fas ligand expression suppresses tumor immune evasion of colon cancer in vivo

Fas ligand (FasL/CD95L) is a transmembrane protein belonging to the tumor necrosis factor superfamily that can trigger apoptotic cell death following ligation to its receptor, Fas (CD95/APO-1). Expression of FasL may help to maintain tumor cells in a state of immune privilege by inducing apoptosis o...

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