A three-year follow-up study of patients with the respiratory subtype of panic disorder after treatment with clonazepam
The demographic, clinical and therapeutic features of the respiratory subtype of panic disorder (PD) versus the non-respiratory subtype were studied in a prospective design. Sixty-seven PD outpatients (DSM-IV), who had previously been categorized into respiratory ( n = 35) and non-respiratory ( n =...
Gespeichert in:
| Veröffentlicht in: | Psychiatry research 2005-11, Vol.137 (1), p.61-70 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 70 |
|---|---|
| container_issue | 1 |
| container_start_page | 61 |
| container_title | Psychiatry research |
| container_volume | 137 |
| creator | Nardi, Antonio E. Valença, Alexandre M. Nascimento, Isabella Lopes, Fabiana L. Mezzasalma, Marco A. Freire, Rafael C. Veras, André B. Zin, Walter A. Versiani, Marcio |
| description | The demographic, clinical and therapeutic features of the respiratory subtype of panic disorder (PD) versus the non-respiratory subtype were studied in a prospective design. Sixty-seven PD outpatients (DSM-IV), who had previously been categorized into respiratory (
n
=
35) and non-respiratory (
n
=
32) subgroups, were openly treated with clonazepam for a 3-year period. The principal measure of efficacy was the number of panic attacks, obtained from the Sheehan Panic and Anticipatory Anxiety Scale. In the first 8 weeks of treatment (acute phase), the respiratory subtype group had a significantly faster response to clonazepam. During the follow-up (weeks 12-156), the two subgroups did not differ significantly in the number of panic attacks experienced from baseline to end point. Patients in the respiratory subtype were characterized by a later onset of disorder and a family history of PD. Patients in the non-respiratory subgroup had a significantly higher number of past depressive episodes than those in the respiratory subgroup. The respiratory subgroup had a faster response after 8 weeks of treatment and an equivalent response in the 3-year follow-up period. Clonazepam had a sustained therapeutic effect over the entire treatment period. |
| doi_str_mv | 10.1016/j.psychres.2005.05.011 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68749924</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0165178105002015</els_id><sourcerecordid>68749924</sourcerecordid><originalsourceid>FETCH-LOGICAL-c396t-a8f7bdf657ceafd55d48afc4fbdde1a03abab572e9035a3d2d2b6de1089e69b83</originalsourceid><addsrcrecordid>eNqFkMFu1DAQhi0EotvCK1S-wC2L7ayT-EZVFahUiQucrYk9Vr1K4mA7rMLT41UW9Yg0mjn4-2esj5Bbzvac8ebTcT-n1TxHTHvBmNyfi_NXZMe7VlQtF_VrsiugrHjb8StyndKRMSa4Um_JFW-EaDouduR0R3PZgtWKEKkLwxBO1TLTlBe70uDoDNnjlBM9-fxcWKTl5uwj5BBXmpY-rzNu4OQNtT6FaDFScLn0HBHyWPJb3Axhgj84w_iOvHEwJHx_mTfk55eHH_ffqqfvXx_v754qU6smV9C5treuka1BcFZKe-jAmYPrrUUOrIYeetkKVKyWUFthRd-UF9YpbFTf1Tfk47Z3juHXginr0SeDwwAThiXppmsPSolDAZsNNDGkFNHpOfoR4qo502fl-qj_Kddn5fpcnJfg7eXC0o9oX2IXxwX4cAEgGRhchMn49MK1olaSycJ93jgsPn57jDqZot6g9RFN1jb4__3lL0wlp1U</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68749924</pqid></control><display><type>article</type><title>A three-year follow-up study of patients with the respiratory subtype of panic disorder after treatment with clonazepam</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Nardi, Antonio E. ; Valença, Alexandre M. ; Nascimento, Isabella ; Lopes, Fabiana L. ; Mezzasalma, Marco A. ; Freire, Rafael C. ; Veras, André B. ; Zin, Walter A. ; Versiani, Marcio</creator><creatorcontrib>Nardi, Antonio E. ; Valença, Alexandre M. ; Nascimento, Isabella ; Lopes, Fabiana L. ; Mezzasalma, Marco A. ; Freire, Rafael C. ; Veras, André B. ; Zin, Walter A. ; Versiani, Marcio</creatorcontrib><description>The demographic, clinical and therapeutic features of the respiratory subtype of panic disorder (PD) versus the non-respiratory subtype were studied in a prospective design. Sixty-seven PD outpatients (DSM-IV), who had previously been categorized into respiratory (
n
=
35) and non-respiratory (
n
=
32) subgroups, were openly treated with clonazepam for a 3-year period. The principal measure of efficacy was the number of panic attacks, obtained from the Sheehan Panic and Anticipatory Anxiety Scale. In the first 8 weeks of treatment (acute phase), the respiratory subtype group had a significantly faster response to clonazepam. During the follow-up (weeks 12-156), the two subgroups did not differ significantly in the number of panic attacks experienced from baseline to end point. Patients in the respiratory subtype were characterized by a later onset of disorder and a family history of PD. Patients in the non-respiratory subgroup had a significantly higher number of past depressive episodes than those in the respiratory subgroup. The respiratory subgroup had a faster response after 8 weeks of treatment and an equivalent response in the 3-year follow-up period. Clonazepam had a sustained therapeutic effect over the entire treatment period.</description><identifier>ISSN: 0165-1781</identifier><identifier>EISSN: 1872-7123</identifier><identifier>DOI: 10.1016/j.psychres.2005.05.011</identifier><identifier>PMID: 16226812</identifier><identifier>CODEN: PSRSDR</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Adult ; Adult and adolescent clinical studies ; Anticonvulsants - therapeutic use ; Anxiety disorder ; Anxiety disorders. Neuroses ; Benzodiazepine ; Biological and medical sciences ; Clonazepam - therapeutic use ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Female ; Follow-up ; Follow-Up Studies ; GABA Modulators - therapeutic use ; Humans ; Male ; Medical sciences ; Middle Aged ; Neuropharmacology ; Panic attack ; Panic disorder ; Panic Disorder - diagnosis ; Panic Disorder - drug therapy ; Panic Disorder - genetics ; Panic Disorder - psychology ; Pharmacology. Drug treatments ; Prospective Studies ; Psycholeptics: tranquillizer, neuroleptic ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Psychopharmacology ; Respiration ; Respiration - drug effects ; Treatment ; Treatment Outcome</subject><ispartof>Psychiatry research, 2005-11, Vol.137 (1), p.61-70</ispartof><rights>2005 Elsevier Ireland Ltd</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-a8f7bdf657ceafd55d48afc4fbdde1a03abab572e9035a3d2d2b6de1089e69b83</citedby><cites>FETCH-LOGICAL-c396t-a8f7bdf657ceafd55d48afc4fbdde1a03abab572e9035a3d2d2b6de1089e69b83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.psychres.2005.05.011$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17239505$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16226812$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nardi, Antonio E.</creatorcontrib><creatorcontrib>Valença, Alexandre M.</creatorcontrib><creatorcontrib>Nascimento, Isabella</creatorcontrib><creatorcontrib>Lopes, Fabiana L.</creatorcontrib><creatorcontrib>Mezzasalma, Marco A.</creatorcontrib><creatorcontrib>Freire, Rafael C.</creatorcontrib><creatorcontrib>Veras, André B.</creatorcontrib><creatorcontrib>Zin, Walter A.</creatorcontrib><creatorcontrib>Versiani, Marcio</creatorcontrib><title>A three-year follow-up study of patients with the respiratory subtype of panic disorder after treatment with clonazepam</title><title>Psychiatry research</title><addtitle>Psychiatry Res</addtitle><description>The demographic, clinical and therapeutic features of the respiratory subtype of panic disorder (PD) versus the non-respiratory subtype were studied in a prospective design. Sixty-seven PD outpatients (DSM-IV), who had previously been categorized into respiratory (
n
=
35) and non-respiratory (
n
=
32) subgroups, were openly treated with clonazepam for a 3-year period. The principal measure of efficacy was the number of panic attacks, obtained from the Sheehan Panic and Anticipatory Anxiety Scale. In the first 8 weeks of treatment (acute phase), the respiratory subtype group had a significantly faster response to clonazepam. During the follow-up (weeks 12-156), the two subgroups did not differ significantly in the number of panic attacks experienced from baseline to end point. Patients in the respiratory subtype were characterized by a later onset of disorder and a family history of PD. Patients in the non-respiratory subgroup had a significantly higher number of past depressive episodes than those in the respiratory subgroup. The respiratory subgroup had a faster response after 8 weeks of treatment and an equivalent response in the 3-year follow-up period. Clonazepam had a sustained therapeutic effect over the entire treatment period.</description><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Anticonvulsants - therapeutic use</subject><subject>Anxiety disorder</subject><subject>Anxiety disorders. Neuroses</subject><subject>Benzodiazepine</subject><subject>Biological and medical sciences</subject><subject>Clonazepam - therapeutic use</subject><subject>Dose-Response Relationship, Drug</subject><subject>Drug Administration Schedule</subject><subject>Female</subject><subject>Follow-up</subject><subject>Follow-Up Studies</subject><subject>GABA Modulators - therapeutic use</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neuropharmacology</subject><subject>Panic attack</subject><subject>Panic disorder</subject><subject>Panic Disorder - diagnosis</subject><subject>Panic Disorder - drug therapy</subject><subject>Panic Disorder - genetics</subject><subject>Panic Disorder - psychology</subject><subject>Pharmacology. Drug treatments</subject><subject>Prospective Studies</subject><subject>Psycholeptics: tranquillizer, neuroleptic</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychopharmacology</subject><subject>Respiration</subject><subject>Respiration - drug effects</subject><subject>Treatment</subject><subject>Treatment Outcome</subject><issn>0165-1781</issn><issn>1872-7123</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMFu1DAQhi0EotvCK1S-wC2L7ayT-EZVFahUiQucrYk9Vr1K4mA7rMLT41UW9Yg0mjn4-2esj5Bbzvac8ebTcT-n1TxHTHvBmNyfi_NXZMe7VlQtF_VrsiugrHjb8StyndKRMSa4Um_JFW-EaDouduR0R3PZgtWKEKkLwxBO1TLTlBe70uDoDNnjlBM9-fxcWKTl5uwj5BBXmpY-rzNu4OQNtT6FaDFScLn0HBHyWPJb3Axhgj84w_iOvHEwJHx_mTfk55eHH_ffqqfvXx_v754qU6smV9C5treuka1BcFZKe-jAmYPrrUUOrIYeetkKVKyWUFthRd-UF9YpbFTf1Tfk47Z3juHXginr0SeDwwAThiXppmsPSolDAZsNNDGkFNHpOfoR4qo502fl-qj_Kddn5fpcnJfg7eXC0o9oX2IXxwX4cAEgGRhchMn49MK1olaSycJ93jgsPn57jDqZot6g9RFN1jb4__3lL0wlp1U</recordid><startdate>20051115</startdate><enddate>20051115</enddate><creator>Nardi, Antonio E.</creator><creator>Valença, Alexandre M.</creator><creator>Nascimento, Isabella</creator><creator>Lopes, Fabiana L.</creator><creator>Mezzasalma, Marco A.</creator><creator>Freire, Rafael C.</creator><creator>Veras, André B.</creator><creator>Zin, Walter A.</creator><creator>Versiani, Marcio</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20051115</creationdate><title>A three-year follow-up study of patients with the respiratory subtype of panic disorder after treatment with clonazepam</title><author>Nardi, Antonio E. ; Valença, Alexandre M. ; Nascimento, Isabella ; Lopes, Fabiana L. ; Mezzasalma, Marco A. ; Freire, Rafael C. ; Veras, André B. ; Zin, Walter A. ; Versiani, Marcio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-a8f7bdf657ceafd55d48afc4fbdde1a03abab572e9035a3d2d2b6de1089e69b83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Anticonvulsants - therapeutic use</topic><topic>Anxiety disorder</topic><topic>Anxiety disorders. Neuroses</topic><topic>Benzodiazepine</topic><topic>Biological and medical sciences</topic><topic>Clonazepam - therapeutic use</topic><topic>Dose-Response Relationship, Drug</topic><topic>Drug Administration Schedule</topic><topic>Female</topic><topic>Follow-up</topic><topic>Follow-Up Studies</topic><topic>GABA Modulators - therapeutic use</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neuropharmacology</topic><topic>Panic attack</topic><topic>Panic disorder</topic><topic>Panic Disorder - diagnosis</topic><topic>Panic Disorder - drug therapy</topic><topic>Panic Disorder - genetics</topic><topic>Panic Disorder - psychology</topic><topic>Pharmacology. Drug treatments</topic><topic>Prospective Studies</topic><topic>Psycholeptics: tranquillizer, neuroleptic</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Psychopharmacology</topic><topic>Respiration</topic><topic>Respiration - drug effects</topic><topic>Treatment</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nardi, Antonio E.</creatorcontrib><creatorcontrib>Valença, Alexandre M.</creatorcontrib><creatorcontrib>Nascimento, Isabella</creatorcontrib><creatorcontrib>Lopes, Fabiana L.</creatorcontrib><creatorcontrib>Mezzasalma, Marco A.</creatorcontrib><creatorcontrib>Freire, Rafael C.</creatorcontrib><creatorcontrib>Veras, André B.</creatorcontrib><creatorcontrib>Zin, Walter A.</creatorcontrib><creatorcontrib>Versiani, Marcio</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Psychiatry research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nardi, Antonio E.</au><au>Valença, Alexandre M.</au><au>Nascimento, Isabella</au><au>Lopes, Fabiana L.</au><au>Mezzasalma, Marco A.</au><au>Freire, Rafael C.</au><au>Veras, André B.</au><au>Zin, Walter A.</au><au>Versiani, Marcio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A three-year follow-up study of patients with the respiratory subtype of panic disorder after treatment with clonazepam</atitle><jtitle>Psychiatry research</jtitle><addtitle>Psychiatry Res</addtitle><date>2005-11-15</date><risdate>2005</risdate><volume>137</volume><issue>1</issue><spage>61</spage><epage>70</epage><pages>61-70</pages><issn>0165-1781</issn><eissn>1872-7123</eissn><coden>PSRSDR</coden><abstract>The demographic, clinical and therapeutic features of the respiratory subtype of panic disorder (PD) versus the non-respiratory subtype were studied in a prospective design. Sixty-seven PD outpatients (DSM-IV), who had previously been categorized into respiratory (
n
=
35) and non-respiratory (
n
=
32) subgroups, were openly treated with clonazepam for a 3-year period. The principal measure of efficacy was the number of panic attacks, obtained from the Sheehan Panic and Anticipatory Anxiety Scale. In the first 8 weeks of treatment (acute phase), the respiratory subtype group had a significantly faster response to clonazepam. During the follow-up (weeks 12-156), the two subgroups did not differ significantly in the number of panic attacks experienced from baseline to end point. Patients in the respiratory subtype were characterized by a later onset of disorder and a family history of PD. Patients in the non-respiratory subgroup had a significantly higher number of past depressive episodes than those in the respiratory subgroup. The respiratory subgroup had a faster response after 8 weeks of treatment and an equivalent response in the 3-year follow-up period. Clonazepam had a sustained therapeutic effect over the entire treatment period.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>16226812</pmid><doi>10.1016/j.psychres.2005.05.011</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0165-1781 |
| ispartof | Psychiatry research, 2005-11, Vol.137 (1), p.61-70 |
| issn | 0165-1781 1872-7123 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68749924 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Adult Adult and adolescent clinical studies Anticonvulsants - therapeutic use Anxiety disorder Anxiety disorders. Neuroses Benzodiazepine Biological and medical sciences Clonazepam - therapeutic use Dose-Response Relationship, Drug Drug Administration Schedule Female Follow-up Follow-Up Studies GABA Modulators - therapeutic use Humans Male Medical sciences Middle Aged Neuropharmacology Panic attack Panic disorder Panic Disorder - diagnosis Panic Disorder - drug therapy Panic Disorder - genetics Panic Disorder - psychology Pharmacology. Drug treatments Prospective Studies Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychopharmacology Respiration Respiration - drug effects Treatment Treatment Outcome |
| title | A three-year follow-up study of patients with the respiratory subtype of panic disorder after treatment with clonazepam |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T08%3A09%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20three-year%20follow-up%20study%20of%20patients%20with%20the%20respiratory%20subtype%20of%20panic%20disorder%20after%20treatment%20with%20clonazepam&rft.jtitle=Psychiatry%20research&rft.au=Nardi,%20Antonio%20E.&rft.date=2005-11-15&rft.volume=137&rft.issue=1&rft.spage=61&rft.epage=70&rft.pages=61-70&rft.issn=0165-1781&rft.eissn=1872-7123&rft.coden=PSRSDR&rft_id=info:doi/10.1016/j.psychres.2005.05.011&rft_dat=%3Cproquest_cross%3E68749924%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68749924&rft_id=info:pmid/16226812&rft_els_id=S0165178105002015&rfr_iscdi=true |