Atomic force microscopy of collagen structure in bone and dentine revealed by osteoclastic resorption

Mineralised tissues such as bone consist of two material phases: collagen protein fibrils, secreted by osteoblasts, form model structures for subsequent deposition of mineral, calcium hydroxyapatite. Collagen and mineral are removed in a three-dimensional manner by osteoclasts during bone turnover i...

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Veröffentlicht in:	Ultramicroscopy 2005-11, Vol.105 (1), p.79-89
Hauptverfasser:	Bozec, Laurent, Groot, Jaco de, Odlyha, Marianne, Nicholls, Brian, Nesbitt, Stephen, Flanagan, Adrienne, Horton, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase Animals Atomic force microscopy (AFM) Bone Bone and Bones - ultrastructure Bone Resorption - metabolism Collagen Collagen - ultrastructure Dentin - ultrastructure Dentine Fluorescent Antibody Technique Humans Isoenzymes Microscopy, Atomic Force Microscopy, Confocal Microscopy, Electron, Scanning Osteoclast Osteoclasts - metabolism Osteoclasts - ultrastructure Rabbits Resorption lacunae Tartrate-Resistant Acid Phosphatase
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