A Novel System for Organ and Tissues Preservation: The Refrigerating Hyperbaric Chamber
This study was designed to investigate the feasibility of building a simple and inexpensive device to preserve organs or tissues in hyperbaric and hypothermic conditions. The device was built on a 40-cm wide, 28-cm long, and 23-cm deep stainless steel chassis. The pressure vessel was built by a 7.8-...
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| Veröffentlicht in: | Transplantation proceedings 2006-07, Vol.38 (6), p.1879-1882 |
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| creator | Guimarães, F.A.G. Taha, M.O. Simões, M.J. Moino, C.A.A. Santos, I.V. Amador, J.C. Santos, R.A. Queiroz, R.B. Amaro, R.R. Jesus, M.A.S. |
| description | This study was designed to investigate the feasibility of building a simple and inexpensive device to preserve organs or tissues in hyperbaric and hypothermic conditions.
The device was built on a 40-cm wide, 28-cm long, and 23-cm deep stainless steel chassis. The pressure vessel was built by a 7.8-cm bore stainless steel cylinder put inside another 12-cm cylinder welded together and closed by a steel plate on the top and bottom. The inferior plate was welded, and the superior one was fixed by manual clasp nut. The cooling system is made up of air compressor, condenser, expansion area, and cooling worm that is located between the cylinders. The temperature-controlling device is a computer processor contained in an integrated-circuit chip, with a on-off system to maintain the chamber temperature between 2° to 4°C. The compression of the chamber is performed by lateral coupling with the oxygen cylinder and is maintained at 5.5 absolute atmospheres and controlled by air pressure gauge. The maximal work pressure was evaluated by spreadsheet. Temperature or pressure changes were evaluated by 12- and 24-hour assays.
The maximal work pressure permitted was 6.5 absolute atmospheres. Thus, the container was free from danger. The temperature inside the chamber was kept between 2° and 4°C. The production costs of the prototype was US$1000.
The manufacture of the refrigerating hyperbaric chamber is viable, simple, and inexpensive. |
| doi_str_mv | 10.1016/j.transproceed.2006.06.054 |
| format | Article |
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The device was built on a 40-cm wide, 28-cm long, and 23-cm deep stainless steel chassis. The pressure vessel was built by a 7.8-cm bore stainless steel cylinder put inside another 12-cm cylinder welded together and closed by a steel plate on the top and bottom. The inferior plate was welded, and the superior one was fixed by manual clasp nut. The cooling system is made up of air compressor, condenser, expansion area, and cooling worm that is located between the cylinders. The temperature-controlling device is a computer processor contained in an integrated-circuit chip, with a on-off system to maintain the chamber temperature between 2° to 4°C. The compression of the chamber is performed by lateral coupling with the oxygen cylinder and is maintained at 5.5 absolute atmospheres and controlled by air pressure gauge. The maximal work pressure was evaluated by spreadsheet. Temperature or pressure changes were evaluated by 12- and 24-hour assays.
The maximal work pressure permitted was 6.5 absolute atmospheres. Thus, the container was free from danger. The temperature inside the chamber was kept between 2° and 4°C. The production costs of the prototype was US$1000.
The manufacture of the refrigerating hyperbaric chamber is viable, simple, and inexpensive.</description><identifier>ISSN: 0041-1345</identifier><identifier>EISSN: 1873-2623</identifier><identifier>DOI: 10.1016/j.transproceed.2006.06.054</identifier><identifier>PMID: 16908312</identifier><identifier>CODEN: TRPPA8</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Biological and medical sciences ; Cold Temperature ; Equipment Design ; Fundamental and applied biological sciences. Psychology ; Fundamental immunology ; Hyperbaric Oxygenation - instrumentation ; Hyperbaric Oxygenation - methods ; Medical sciences ; Organ Preservation - instrumentation ; Organ Preservation - methods ; Refrigeration ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Temperature ; Tissue, organ and graft immunology</subject><ispartof>Transplantation proceedings, 2006-07, Vol.38 (6), p.1879-1882</ispartof><rights>2006 Elsevier Inc.</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-fd6dd24854fba718352ee53cdbc61c3473d1756922a9401c680b80e5eea3f0513</citedby><cites>FETCH-LOGICAL-c408t-fd6dd24854fba718352ee53cdbc61c3473d1756922a9401c680b80e5eea3f0513</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.transproceed.2006.06.054$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>309,310,314,780,784,789,790,3550,23930,23931,25140,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18070471$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16908312$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Guimarães, F.A.G.</creatorcontrib><creatorcontrib>Taha, M.O.</creatorcontrib><creatorcontrib>Simões, M.J.</creatorcontrib><creatorcontrib>Moino, C.A.A.</creatorcontrib><creatorcontrib>Santos, I.V.</creatorcontrib><creatorcontrib>Amador, J.C.</creatorcontrib><creatorcontrib>Santos, R.A.</creatorcontrib><creatorcontrib>Queiroz, R.B.</creatorcontrib><creatorcontrib>Amaro, R.R.</creatorcontrib><creatorcontrib>Jesus, M.A.S.</creatorcontrib><title>A Novel System for Organ and Tissues Preservation: The Refrigerating Hyperbaric Chamber</title><title>Transplantation proceedings</title><addtitle>Transplant Proc</addtitle><description>This study was designed to investigate the feasibility of building a simple and inexpensive device to preserve organs or tissues in hyperbaric and hypothermic conditions.
The device was built on a 40-cm wide, 28-cm long, and 23-cm deep stainless steel chassis. The pressure vessel was built by a 7.8-cm bore stainless steel cylinder put inside another 12-cm cylinder welded together and closed by a steel plate on the top and bottom. The inferior plate was welded, and the superior one was fixed by manual clasp nut. The cooling system is made up of air compressor, condenser, expansion area, and cooling worm that is located between the cylinders. The temperature-controlling device is a computer processor contained in an integrated-circuit chip, with a on-off system to maintain the chamber temperature between 2° to 4°C. The compression of the chamber is performed by lateral coupling with the oxygen cylinder and is maintained at 5.5 absolute atmospheres and controlled by air pressure gauge. The maximal work pressure was evaluated by spreadsheet. Temperature or pressure changes were evaluated by 12- and 24-hour assays.
The maximal work pressure permitted was 6.5 absolute atmospheres. Thus, the container was free from danger. The temperature inside the chamber was kept between 2° and 4°C. The production costs of the prototype was US$1000.
The manufacture of the refrigerating hyperbaric chamber is viable, simple, and inexpensive.</description><subject>Biological and medical sciences</subject><subject>Cold Temperature</subject><subject>Equipment Design</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Fundamental immunology</subject><subject>Hyperbaric Oxygenation - instrumentation</subject><subject>Hyperbaric Oxygenation - methods</subject><subject>Medical sciences</subject><subject>Organ Preservation - instrumentation</subject><subject>Organ Preservation - methods</subject><subject>Refrigeration</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Temperature</subject><subject>Tissue, organ and graft immunology</subject><issn>0041-1345</issn><issn>1873-2623</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkF1LHDEUhoO06Gr7FyQI9W62-Z6sd7LWWhCVutLLkEnOrFnmY01mF_bfN8Mu2svCgZDkOee8PAhdUDKlhKrvq-kQbZfWsXcAfsoIUdOxpDhCE6pLXjDF-Cc0IUTQgnIhT9BpSiuS70zwY3RC1YxoTtkE_bnGD_0WGvy8SwO0uO4jfoxL22HbebwIKW0g4acICeLWDqHvrvDiFfBvqGNYQsxP3RLf7dYQKxuDw_NX21YQv6DPtW0SfD2cZ-jl9sdiflfcP_78Nb--L5wgeihqr7xnQktRV7akmksGILnzlVPUcVFyT0upZozZmSDUKU0qTUACWF4TSfkZutzPzTbectTBtCE5aBrbQb9JRulSKKJEBq_2oIt9ShFqs46htXFnKDGjVrMy_2o1o1Yzlhybzw9bNlWb_95bDx4z8O0A2ORsU-dBLqQPTpOSiHKMe7PnIDvZBogmuQCdAx8iuMH4PvxPnr93iZzl</recordid><startdate>20060701</startdate><enddate>20060701</enddate><creator>Guimarães, F.A.G.</creator><creator>Taha, M.O.</creator><creator>Simões, M.J.</creator><creator>Moino, C.A.A.</creator><creator>Santos, I.V.</creator><creator>Amador, J.C.</creator><creator>Santos, R.A.</creator><creator>Queiroz, R.B.</creator><creator>Amaro, R.R.</creator><creator>Jesus, M.A.S.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20060701</creationdate><title>A Novel System for Organ and Tissues Preservation: The Refrigerating Hyperbaric Chamber</title><author>Guimarães, F.A.G. ; Taha, M.O. ; Simões, M.J. ; Moino, C.A.A. ; Santos, I.V. ; Amador, J.C. ; Santos, R.A. ; Queiroz, R.B. ; Amaro, R.R. ; Jesus, M.A.S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c408t-fd6dd24854fba718352ee53cdbc61c3473d1756922a9401c680b80e5eea3f0513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Biological and medical sciences</topic><topic>Cold Temperature</topic><topic>Equipment Design</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Fundamental immunology</topic><topic>Hyperbaric Oxygenation - instrumentation</topic><topic>Hyperbaric Oxygenation - methods</topic><topic>Medical sciences</topic><topic>Organ Preservation - instrumentation</topic><topic>Organ Preservation - methods</topic><topic>Refrigeration</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Temperature</topic><topic>Tissue, organ and graft immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Guimarães, F.A.G.</creatorcontrib><creatorcontrib>Taha, M.O.</creatorcontrib><creatorcontrib>Simões, M.J.</creatorcontrib><creatorcontrib>Moino, C.A.A.</creatorcontrib><creatorcontrib>Santos, I.V.</creatorcontrib><creatorcontrib>Amador, J.C.</creatorcontrib><creatorcontrib>Santos, R.A.</creatorcontrib><creatorcontrib>Queiroz, R.B.</creatorcontrib><creatorcontrib>Amaro, R.R.</creatorcontrib><creatorcontrib>Jesus, M.A.S.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Transplantation proceedings</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Guimarães, F.A.G.</au><au>Taha, M.O.</au><au>Simões, M.J.</au><au>Moino, C.A.A.</au><au>Santos, I.V.</au><au>Amador, J.C.</au><au>Santos, R.A.</au><au>Queiroz, R.B.</au><au>Amaro, R.R.</au><au>Jesus, M.A.S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Novel System for Organ and Tissues Preservation: The Refrigerating Hyperbaric Chamber</atitle><jtitle>Transplantation proceedings</jtitle><addtitle>Transplant Proc</addtitle><date>2006-07-01</date><risdate>2006</risdate><volume>38</volume><issue>6</issue><spage>1879</spage><epage>1882</epage><pages>1879-1882</pages><issn>0041-1345</issn><eissn>1873-2623</eissn><coden>TRPPA8</coden><abstract>This study was designed to investigate the feasibility of building a simple and inexpensive device to preserve organs or tissues in hyperbaric and hypothermic conditions.
The device was built on a 40-cm wide, 28-cm long, and 23-cm deep stainless steel chassis. The pressure vessel was built by a 7.8-cm bore stainless steel cylinder put inside another 12-cm cylinder welded together and closed by a steel plate on the top and bottom. The inferior plate was welded, and the superior one was fixed by manual clasp nut. The cooling system is made up of air compressor, condenser, expansion area, and cooling worm that is located between the cylinders. The temperature-controlling device is a computer processor contained in an integrated-circuit chip, with a on-off system to maintain the chamber temperature between 2° to 4°C. The compression of the chamber is performed by lateral coupling with the oxygen cylinder and is maintained at 5.5 absolute atmospheres and controlled by air pressure gauge. The maximal work pressure was evaluated by spreadsheet. Temperature or pressure changes were evaluated by 12- and 24-hour assays.
The maximal work pressure permitted was 6.5 absolute atmospheres. Thus, the container was free from danger. The temperature inside the chamber was kept between 2° and 4°C. The production costs of the prototype was US$1000.
The manufacture of the refrigerating hyperbaric chamber is viable, simple, and inexpensive.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>16908312</pmid><doi>10.1016/j.transproceed.2006.06.054</doi><tpages>4</tpages></addata></record> |
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| ispartof | Transplantation proceedings, 2006-07, Vol.38 (6), p.1879-1882 |
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| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Biological and medical sciences Cold Temperature Equipment Design Fundamental and applied biological sciences. Psychology Fundamental immunology Hyperbaric Oxygenation - instrumentation Hyperbaric Oxygenation - methods Medical sciences Organ Preservation - instrumentation Organ Preservation - methods Refrigeration Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Temperature Tissue, organ and graft immunology |
| title | A Novel System for Organ and Tissues Preservation: The Refrigerating Hyperbaric Chamber |
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