Polymorphisms of the BRCA2 and RAD51 genes in breast cancer

We performed a case-control study (150 cases and 150 controls) to test the association between three polymorphisms in BRCA2 and RAD51 genes and breast cancer risk. Genotypes were determined in DNA from blood cells by PCR-RFLP. Cancer occurrence was strongly associated with the BRCA2 Met/1915Thr homo...

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Veröffentlicht in:	Breast cancer research and treatment 2005-11, Vol.94 (2), p.105-109
Hauptverfasser:	SLIWINSKI, Tomasz, KRUPA, Renata, MAJSTEREK, Ireneusz, RYKALA, Jan, KOLACINSKA, Agnieszka, MORAWIEC, Zbigniew, DRZEWOSKI, Jozef, ZADROZNY, Marek, BLASIAK, Janusz
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences BRCA2 Protein - genetics Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer research Cancer therapies Carcinoma, Intraductal, Noninfiltrating - genetics Carcinoma, Intraductal, Noninfiltrating - pathology Case-Control Studies DNA - analysis European Continental Ancestry Group - genetics Female Genes Genotype Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Middle Aged Poland Polymerase Chain Reaction Polymorphism Polymorphism, Genetic Rad51 Recombinase - genetics Risk assessment Tumors
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