Dopamine Receptor Oligomerization Visualized in Living Cells

G protein-coupled receptors occur as dimers within arrays of oligomers. We visualized ensembles of dopamine receptor oligomers in living cells and evaluated the contributions of receptor conformation to the dynamics of oligomer association and dissociation, using a strategy of trafficking a receptor...

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Veröffentlicht in:	The Journal of biological chemistry 2005-11, Vol.280 (44), p.37225-37235
Hauptverfasser:	O'Dowd, Brian F., Ji, Xiaodong, Alijaniaram, Mohammad, Rajaram, Ryan D., Kong, Michael M.C., Rashid, Asim, Nguyen, Tuan, George, Susan R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Butaclamol - metabolism Cell Nucleus - metabolism Cells, Cultured - cytology Cells, Cultured - metabolism Dimerization Dopamine - metabolism Dopamine Antagonists - metabolism Green Fluorescent Proteins - metabolism Humans Kidney - metabolism Nuclear Localization Signals Protein Conformation Receptors, Dopamine D1 - agonists Receptors, Dopamine D1 - chemistry Receptors, Dopamine D1 - metabolism Receptors, Dopamine D2 - agonists Receptors, Dopamine D2 - chemistry Receptors, Dopamine D2 - metabolism Recombinant Fusion Proteins - metabolism
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