β-Catenin Status Predicts a Favorable Outcome in Childhood Medulloblastoma: The United Kingdom Children's Cancer Study Group Brain Tumour Committee

Identifying pathobiological correlates of clinical behavior or therapeutic response currently represents a key challenge for medulloblastoma research. Nuclear accumulation of the beta-catenin protein is associated with activation of the Wnt/Wg signaling pathway, and mutations affecting components of...

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Veröffentlicht in:	Journal of clinical oncology 2005-11, Vol.23 (31), p.7951-7957
Hauptverfasser:	ELLISON, David W, ONILUDE, Olabisi E, LINDSEY, Janet C, LUSHER, Meryl E, WESTON, Claire L, TAYLOR, Roger E, PEARSON, Andrew D, CLIFFORD, Steven C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenomatous Polyposis Coli Protein - metabolism Adolescent beta Catenin - genetics beta Catenin - metabolism Biological and medical sciences Cell Nucleus - metabolism Cerebellar Neoplasms - metabolism Cerebellar Neoplasms - mortality Cerebellar Neoplasms - pathology Child Child, Preschool Cytoplasm - metabolism Cytoplasm - pathology DNA Mutational Analysis Female Humans Immunoenzyme Techniques Male Medical sciences Medulloblastoma - metabolism Medulloblastoma - mortality Medulloblastoma - pathology Mutation Neurology Polymerase Chain Reaction Prognosis Survival Rate Tumors Tumors of the nervous system. Phacomatoses United Kingdom
Online-Zugang:	Volltext
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