Infectious tolerance and the long-term acceptance of transplanted tissue

Short courses of antibody treatment aimed at blocking the coreceptors CD4 and CD8 and/or costimulatory molecules such as CD40L are able to bring about long‐term acceptance and tolerance of allogeneic transplants. This tolerant state is operational, in that potential effector cells remain but are tig...

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Veröffentlicht in:	Immunological reviews 2006-08, Vol.212 (1), p.301-313
Hauptverfasser:	Waldmann, Herman, Adams, Elizabeth, Fairchild, Paul, Cobbold, Stephen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Graft Rejection - immunology Graft Rejection - microbiology Graft Rejection - prevention & control Graft Survival - immunology Infections - immunology Infections - therapy infectious tolerance Mice privilege regulation regulatory T cell T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - transplantation tolerance Transplantation Tolerance - immunology
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