Gender differences in lipoprotein metabolism and dietary response: basis in hormonal differences and implications for cardiovascular disease
The transport of fat in the blood stream is approximately twice as fast in women as men. Disease states such as obesity and diabetes are associated with greater lipoprotein abnormalities in women compared with men. A greater increment in cardiovascular disease risk in women is linked to these abnorm...
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| Veröffentlicht in: | Current atherosclerosis reports 2005-11, Vol.7 (6), p.472-479 |
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| container_title | Current atherosclerosis reports |
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| creator | Knopp, Robert H Paramsothy, Pathmaja Retzlaff, Barbara M Fish, Brian Walden, Carolyn Dowdy, Alice Tsunehara, Christine Aikawa, Keiko Cheung, Marian C |
| description | The transport of fat in the blood stream is approximately twice as fast in women as men. Disease states such as obesity and diabetes are associated with greater lipoprotein abnormalities in women compared with men. A greater increment in cardiovascular disease risk in women is linked to these abnormalities. A greater change in triglyceride level and a lesser change in low-density lipoprotein are observed in women than men with high-carbohydrate or high-fat feeding. Most consistent are greater changes in high-density lipoprotein (HDL), HDL2, and apolipoprotein A-I levels in women compared with men with high-carbohydrate or high-fat feeding. Dietary fat restriction in women appears to have a less beneficial lipoprotein effect than in men. Dietary fat restriction for heart disease prevention may be less ideal in women than in men. |
| doi_str_mv | 10.1007/s11883-005-0065-6 |
| format | Article |
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| identifier | ISSN: 1523-3804 |
| ispartof | Current atherosclerosis reports, 2005-11, Vol.7 (6), p.472-479 |
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| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Androgens - metabolism Cardiovascular Diseases - diet therapy Cardiovascular Diseases - epidemiology Cardiovascular Diseases - prevention & control Cholesterol, HDL - metabolism Cholesterol, LDL - metabolism Diet Estrogens - metabolism Female Humans Lipid Metabolism - physiology Lipoproteins - metabolism Male Risk Assessment Sensitivity and Specificity Sex Factors |
| title | Gender differences in lipoprotein metabolism and dietary response: basis in hormonal differences and implications for cardiovascular disease |
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