Solid Phase Approaches to N-Heterocycles Using a Sulfur Linker Cleaved by SmI2

A sulfur HASC (α-hetero-atom substituted carbonyl) linker has been utilized in solid-phase approaches to oxindoles and tetrahydroquinolones. The route to oxindoles employs the first Pummerer cyclizations on solid phase, whereas the route to tetrahydroquinolones involves a microwave-assisted Heck rea...

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Veröffentlicht in:	Journal of organic chemistry 2006-08, Vol.71 (17), p.6497-6507
Hauptverfasser:	McAllister, Laura A, Turner, Kristy L, Brand, Stephen, Stefaniak, Mark, Procter, David J
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Cross-Linking Reagents - chemistry Cyclization Exact sciences and technology Heterocyclic compounds Heterocyclic Compounds - chemical synthesis Heterocyclic Compounds - chemistry Heterocyclic compounds with only one n hetero atom and condensed derivatives Indoles - chemistry Iodides - chemistry Molecular Structure Organic chemistry Preparations and properties Samarium - chemistry Sulfur - chemistry
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