Effect of periconceptional undernutrition and gender on hypothalamic–pituitary–adrenal axis function in young adult sheep

Glucocorticoids are proposed to act as intermediary factors that transcribe the developmental programming sequelae of maternal nutrient restriction (NR). Periconceptional under-nutrition of sheep markedly activates fetal hypothalamic–pituitary–adrenal (HPA) axis activity leading to preterm birth, wh...

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Veröffentlicht in:	Journal of endocrinology 2006-08, Vol.190 (2), p.203-212
Hauptverfasser:	Gardner, D S, Van Bon, B W M, Dandrea, J, Goddard, P J, May, S F, Wilson, V, Stephenson, T, Symonds, M E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenocorticotropic Hormone - blood Animals Arginine Vasopressin Biological and medical sciences Blood Pressure - drug effects Blood Specimen Collection - methods Corticotropin-Releasing Hormone Female Fundamental and applied biological sciences. Psychology Gestational Age Heart Rate - drug effects Hormones and neuropeptides. Regulation Hydrocortisone - blood Hypothalamo-Hypophyseal System - drug effects Hypothalamo-Hypophyseal System - physiology Hypothalamus. Hypophysis. Epiphysis. Urophysis Male Malnutrition - metabolism Maternal Nutritional Physiological Phenomena Pituitary-Adrenal System - drug effects Pituitary-Adrenal System - physiology Pregnancy Regular papers Sex Sheep - growth & development Sheep - metabolism Vertebrates: endocrinology
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