Insertion-Deletion Polymorphism in the Angiotensin-Converting Enzyme (ACE) Gene Among Sudanese, Somalis, Emiratis, and Omanis

The angiotensin-converting enzyme (ACE) gene in humans contains an insertion-deletion polymorphism in its intron 16. Because of its involvement with the renin-angiotensin system, the insertion-deletion polymorphism of the ACE gene has been widely investigated in different populations and in case-con...

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Veröffentlicht in:Human biology 2006-02, Vol.78 (1), p.103-108
Hauptverfasser: Bayoumi, Riad A., Simsek, M., Yahya, Taher M., Bendict, Sheela, Al-Hinai, Ali, Al-Barwani, Hameeda, Hassan, M. O.
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Sprache:eng
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Zusammenfassung:The angiotensin-converting enzyme (ACE) gene in humans contains an insertion-deletion polymorphism in its intron 16. Because of its involvement with the renin-angiotensin system, the insertion-deletion polymorphism of the ACE gene has been widely investigated in different populations and in case-control studies. However, similar studies for Arab populations are limited in number. Therefore we have investigated the frequencies of the *I and *D alleles of the ACE gene among Sudanese, Somalis, and Arab nationals of the United Arab Emirates and Oman using previously described methods. Our data indicate a preponderance of the *D allele among the Arab and African populations studied (Sudanese, 0.64; Somalis, 0.73; Emiratis, 0.61; and Omanis, 0.71).
ISSN:0018-7143
1534-6617
1534-6617
DOI:10.1353/hub.2006.0022