The Post-LLETZ cervical smear : Influence of time interval from LLETZ
To determine the effect of the time interval between large loop excision through the transformation zone (LLETZ) and the first subsequent cervical smear on the adequacy of the smear for cytologic interpretation and cytologic abnormality rates. A retrospective, case-note analysis of women attending a...
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Veröffentlicht in: | Acta cytologica 2006-07, Vol.50 (4), p.415-417 |
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container_title | Acta cytologica |
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creator | HUSSEIN, Husswan Yasmin Wan NAIK, Raj TAILOR, Anil EDMONDSON, Richard J CROSS, Paul A DE BARROS LOPES, Alberto GODFREY, Keith A HATEM, Mohammaed H |
description | To determine the effect of the time interval between large loop excision through the transformation zone (LLETZ) and the first subsequent cervical smear on the adequacy of the smear for cytologic interpretation and cytologic abnormality rates.
A retrospective, case-note analysis of women attending a colposcopy clinic between May 1, 1999, and March 31, 2002, who had high grade histologic lesions on their LLETZ biopsy, irrespective of the referral indication.
A total of 771 women were included in the study. Negative smears were reported in 639 (82.9%); 82 (10.6%) were abnormal and 50 (6.5%) unsatisfactory. The post-LLETZ smear was performed at a median interval of 105 days (range, 48-829). A univariate logistic regression analysis did not reveal any relationship between the rate of unsatisfactory or abnormal smears and the interval since having LLETZ (p = 0.935).
These data do not support the traditionally held concept that performing the post-LLETZ smear before 6 months increases the rate of unsatisfactory or abnormal smears. |
doi_str_mv | 10.1159/000325984 |
format | Article |
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A retrospective, case-note analysis of women attending a colposcopy clinic between May 1, 1999, and March 31, 2002, who had high grade histologic lesions on their LLETZ biopsy, irrespective of the referral indication.
A total of 771 women were included in the study. Negative smears were reported in 639 (82.9%); 82 (10.6%) were abnormal and 50 (6.5%) unsatisfactory. The post-LLETZ smear was performed at a median interval of 105 days (range, 48-829). A univariate logistic regression analysis did not reveal any relationship between the rate of unsatisfactory or abnormal smears and the interval since having LLETZ (p = 0.935).
These data do not support the traditionally held concept that performing the post-LLETZ smear before 6 months increases the rate of unsatisfactory or abnormal smears.</description><identifier>ISSN: 0001-5547</identifier><identifier>EISSN: 1938-2650</identifier><identifier>DOI: 10.1159/000325984</identifier><identifier>PMID: 16901006</identifier><identifier>CODEN: ACYTAN</identifier><language>eng</language><publisher>St. Louis, MO: Science Printers and Publishers</publisher><subject>Biological and medical sciences ; Colposcopy ; Female ; Female genital diseases ; Gynecology. Andrology. Obstetrics ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Medical sciences ; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques ; Postoperative Period ; Retrospective Studies ; Time Factors ; Tumors ; Vaginal Smears - methods ; Vaginal Smears - standards</subject><ispartof>Acta cytologica, 2006-07, Vol.50 (4), p.415-417</ispartof><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17954307$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16901006$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HUSSEIN, Husswan Yasmin Wan</creatorcontrib><creatorcontrib>NAIK, Raj</creatorcontrib><creatorcontrib>TAILOR, Anil</creatorcontrib><creatorcontrib>EDMONDSON, Richard J</creatorcontrib><creatorcontrib>CROSS, Paul A</creatorcontrib><creatorcontrib>DE BARROS LOPES, Alberto</creatorcontrib><creatorcontrib>GODFREY, Keith A</creatorcontrib><creatorcontrib>HATEM, Mohammaed H</creatorcontrib><title>The Post-LLETZ cervical smear : Influence of time interval from LLETZ</title><title>Acta cytologica</title><addtitle>Acta Cytol</addtitle><description>To determine the effect of the time interval between large loop excision through the transformation zone (LLETZ) and the first subsequent cervical smear on the adequacy of the smear for cytologic interpretation and cytologic abnormality rates.
A retrospective, case-note analysis of women attending a colposcopy clinic between May 1, 1999, and March 31, 2002, who had high grade histologic lesions on their LLETZ biopsy, irrespective of the referral indication.
A total of 771 women were included in the study. Negative smears were reported in 639 (82.9%); 82 (10.6%) were abnormal and 50 (6.5%) unsatisfactory. The post-LLETZ smear was performed at a median interval of 105 days (range, 48-829). A univariate logistic regression analysis did not reveal any relationship between the rate of unsatisfactory or abnormal smears and the interval since having LLETZ (p = 0.935).
These data do not support the traditionally held concept that performing the post-LLETZ smear before 6 months increases the rate of unsatisfactory or abnormal smears.</description><subject>Biological and medical sciences</subject><subject>Colposcopy</subject><subject>Female</subject><subject>Female genital diseases</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Medical sciences</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</subject><subject>Postoperative Period</subject><subject>Retrospective Studies</subject><subject>Time Factors</subject><subject>Tumors</subject><subject>Vaginal Smears - methods</subject><subject>Vaginal Smears - standards</subject><issn>0001-5547</issn><issn>1938-2650</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFz0tLxDAUBeAgijOOLvwDko3uqjdJ83Inw6gDBV3UjZuS5oGVPsamFfz3Bh1xdeDw3QsHoXMC14RwfQMAjHKt8gO0JJqpjAoOh2iZepJxnssFOonxPSkmBDtGCyI0EACxRJvyzePnIU5ZUWzKV2z9-NlY0-LYeTPiW7ztQzv73no8BDw1ncdNPyWUSBiHDv-cnaKjYNroz_a5Qi_3m3L9mBVPD9v1XZHtKNNT5qVzOndEsdoRF0BxU3stqAJdU_C10jLkTorASQLckmCcNSGnUAseZGArdPX7dzcOH7OPU9U10fq2Nb0f5lgJJZkARRO82MO57ryrdmPTmfGr-huewOUemJjmhtH0ton_TmqeM5DsG0NSZII</recordid><startdate>20060701</startdate><enddate>20060701</enddate><creator>HUSSEIN, Husswan Yasmin Wan</creator><creator>NAIK, Raj</creator><creator>TAILOR, Anil</creator><creator>EDMONDSON, Richard J</creator><creator>CROSS, Paul A</creator><creator>DE BARROS LOPES, Alberto</creator><creator>GODFREY, Keith A</creator><creator>HATEM, Mohammaed H</creator><general>Science Printers and Publishers</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20060701</creationdate><title>The Post-LLETZ cervical smear : Influence of time interval from LLETZ</title><author>HUSSEIN, Husswan Yasmin Wan ; NAIK, Raj ; TAILOR, Anil ; EDMONDSON, Richard J ; CROSS, Paul A ; DE BARROS LOPES, Alberto ; GODFREY, Keith A ; HATEM, Mohammaed H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p239t-e7dd94d183bd1df085abe962809b20eb897f4d76f51bd15c1fadcaf420b65f7f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Biological and medical sciences</topic><topic>Colposcopy</topic><topic>Female</topic><topic>Female genital diseases</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Medical sciences</topic><topic>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</topic><topic>Postoperative Period</topic><topic>Retrospective Studies</topic><topic>Time Factors</topic><topic>Tumors</topic><topic>Vaginal Smears - methods</topic><topic>Vaginal Smears - standards</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HUSSEIN, Husswan Yasmin Wan</creatorcontrib><creatorcontrib>NAIK, Raj</creatorcontrib><creatorcontrib>TAILOR, Anil</creatorcontrib><creatorcontrib>EDMONDSON, Richard J</creatorcontrib><creatorcontrib>CROSS, Paul A</creatorcontrib><creatorcontrib>DE BARROS LOPES, Alberto</creatorcontrib><creatorcontrib>GODFREY, Keith A</creatorcontrib><creatorcontrib>HATEM, Mohammaed H</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Acta cytologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HUSSEIN, Husswan Yasmin Wan</au><au>NAIK, Raj</au><au>TAILOR, Anil</au><au>EDMONDSON, Richard J</au><au>CROSS, Paul A</au><au>DE BARROS LOPES, Alberto</au><au>GODFREY, Keith A</au><au>HATEM, Mohammaed H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Post-LLETZ cervical smear : Influence of time interval from LLETZ</atitle><jtitle>Acta cytologica</jtitle><addtitle>Acta Cytol</addtitle><date>2006-07-01</date><risdate>2006</risdate><volume>50</volume><issue>4</issue><spage>415</spage><epage>417</epage><pages>415-417</pages><issn>0001-5547</issn><eissn>1938-2650</eissn><coden>ACYTAN</coden><abstract>To determine the effect of the time interval between large loop excision through the transformation zone (LLETZ) and the first subsequent cervical smear on the adequacy of the smear for cytologic interpretation and cytologic abnormality rates.
A retrospective, case-note analysis of women attending a colposcopy clinic between May 1, 1999, and March 31, 2002, who had high grade histologic lesions on their LLETZ biopsy, irrespective of the referral indication.
A total of 771 women were included in the study. Negative smears were reported in 639 (82.9%); 82 (10.6%) were abnormal and 50 (6.5%) unsatisfactory. The post-LLETZ smear was performed at a median interval of 105 days (range, 48-829). A univariate logistic regression analysis did not reveal any relationship between the rate of unsatisfactory or abnormal smears and the interval since having LLETZ (p = 0.935).
These data do not support the traditionally held concept that performing the post-LLETZ smear before 6 months increases the rate of unsatisfactory or abnormal smears.</abstract><cop>St. Louis, MO</cop><pub>Science Printers and Publishers</pub><pmid>16901006</pmid><doi>10.1159/000325984</doi><tpages>3</tpages></addata></record> |
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subjects | Biological and medical sciences Colposcopy Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Investigative techniques, diagnostic techniques (general aspects) Medical sciences Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Postoperative Period Retrospective Studies Time Factors Tumors Vaginal Smears - methods Vaginal Smears - standards |
title | The Post-LLETZ cervical smear : Influence of time interval from LLETZ |
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