Anatomical, histological and genetic investigations of a sexually anomalous goat
An apparently female goat was masculine in appearance and had strong male-pattern libido and behaviour. The goat’s DNA was subjected to PCR analysis and its reproductive system was examined anatomically and histologically. The external genitalia consisted of an apparent vulva in the normal position...
Gespeichert in:
| Veröffentlicht in: | Veterinary record 2005-10, Vol.157 (17), p.513-516 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 516 |
|---|---|
| container_issue | 17 |
| container_start_page | 513 |
| container_title | Veterinary record |
| container_volume | 157 |
| creator | Hafez, S. A. Huckle, W. R. Caceci, T. |
| description | An apparently female goat was masculine in appearance and had strong male-pattern libido and behaviour. The goat’s DNA was subjected to PCR analysis and its reproductive system was examined anatomically and histologically. The external genitalia consisted of an apparent vulva in the normal position and a grossly enlarged clitoris. Two masses could be palpated lying subcutaneously in the inguinal region; when they were removed they had the macroscopic appearance of hypoplastic testes, and histologically they had atrophic tubules and prominent interstitial tissues. To exclude sex chimaerism, X and Y chromosome-specific targets were amplified by PCR, using bone marrow and muscle DNA templates. The goat had some Y chromosomespecific sequences such as SRY and BRY.I but lacked others, such as BOV97M. |
| doi_str_mv | 10.1136/vr.157.17.513 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68730545</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4013630941</sourcerecordid><originalsourceid>FETCH-LOGICAL-b4230-640850fff7c27a350c257507c1405f65b12406867eed716c23abc178ff92d5e93</originalsourceid><addsrcrecordid>eNqFkN1rFDEUxYModq0--qoDQvHBWW--dx5raVUoKNr6GjLZZMySmbTJzNb9780wC4IP-nTvhd8593AQeolhjTEV7_dpjblcY7nmmD5CKwKM1FJIeIxWMO-sAThBz3LeAZCGU_IUnWBBGCOUrdDX80GPsfdGh3fVT5_HGGI3X5UetlVnBzt6U_lhb_PoOz36OOQqukpX2f6adAiHAsZehzjlqot6fI6eOB2yfXGcp-j26vLm4lN9_eXj54vz67otj6EWDDYcnHPSEKkpB0O45CANZsCd4C0mDMRGSGu3EgtDqG4NlhvnGrLltqGn6GzxvUvxfirpVO-zsSHowZYsSmwkBc54Ad_8Be7ilIaSTWEpG8Jkw2a7eqFMijkn69Rd8r1OB4VBzUWrfVKl6KJRpejCvzq6Tm1vt3_oY7MFEAvw4IM9_NtN_bi8-fbhCoTAUISvF6HTUeku-axuvxPAFDAwoGIm3i5E2-_-E_M3oiyeAw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1779247949</pqid></control><display><type>article</type><title>Anatomical, histological and genetic investigations of a sexually anomalous goat</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Hafez, S. A. ; Huckle, W. R. ; Caceci, T.</creator><creatorcontrib>Hafez, S. A. ; Huckle, W. R. ; Caceci, T.</creatorcontrib><description>An apparently female goat was masculine in appearance and had strong male-pattern libido and behaviour. The goat’s DNA was subjected to PCR analysis and its reproductive system was examined anatomically and histologically. The external genitalia consisted of an apparent vulva in the normal position and a grossly enlarged clitoris. Two masses could be palpated lying subcutaneously in the inguinal region; when they were removed they had the macroscopic appearance of hypoplastic testes, and histologically they had atrophic tubules and prominent interstitial tissues. To exclude sex chimaerism, X and Y chromosome-specific targets were amplified by PCR, using bone marrow and muscle DNA templates. The goat had some Y chromosomespecific sequences such as SRY and BRY.I but lacked others, such as BOV97M.</description><identifier>ISSN: 0042-4900</identifier><identifier>EISSN: 2042-7670</identifier><identifier>DOI: 10.1136/vr.157.17.513</identifier><identifier>PMID: 16244234</identifier><language>eng</language><publisher>England: BMJ Publishing Group Limited</publisher><subject>Animals ; Diagnosis, Differential ; Disorders of Sex Development - diagnosis ; Disorders of Sex Development - pathology ; Disorders of Sex Development - veterinary ; Female ; genetic techniques and protocols ; Goat Diseases - diagnosis ; Goat Diseases - pathology ; Goats ; Polymerase Chain Reaction - veterinary ; Sex Determination Analysis - veterinary ; sexing ; Y Chromosome - chemistry</subject><ispartof>Veterinary record, 2005-10, Vol.157 (17), p.513-516</ispartof><rights>British Veterinary Association. All rights reserved.</rights><rights>British Veterinary Association 2005</rights><rights>Copyright: 2005 British Veterinary Association. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b4230-640850fff7c27a350c257507c1405f65b12406867eed716c23abc178ff92d5e93</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1136%2Fvr.157.17.513$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1136%2Fvr.157.17.513$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16244234$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hafez, S. A.</creatorcontrib><creatorcontrib>Huckle, W. R.</creatorcontrib><creatorcontrib>Caceci, T.</creatorcontrib><title>Anatomical, histological and genetic investigations of a sexually anomalous goat</title><title>Veterinary record</title><addtitle>Vet Rec</addtitle><description>An apparently female goat was masculine in appearance and had strong male-pattern libido and behaviour. The goat’s DNA was subjected to PCR analysis and its reproductive system was examined anatomically and histologically. The external genitalia consisted of an apparent vulva in the normal position and a grossly enlarged clitoris. Two masses could be palpated lying subcutaneously in the inguinal region; when they were removed they had the macroscopic appearance of hypoplastic testes, and histologically they had atrophic tubules and prominent interstitial tissues. To exclude sex chimaerism, X and Y chromosome-specific targets were amplified by PCR, using bone marrow and muscle DNA templates. The goat had some Y chromosomespecific sequences such as SRY and BRY.I but lacked others, such as BOV97M.</description><subject>Animals</subject><subject>Diagnosis, Differential</subject><subject>Disorders of Sex Development - diagnosis</subject><subject>Disorders of Sex Development - pathology</subject><subject>Disorders of Sex Development - veterinary</subject><subject>Female</subject><subject>genetic techniques and protocols</subject><subject>Goat Diseases - diagnosis</subject><subject>Goat Diseases - pathology</subject><subject>Goats</subject><subject>Polymerase Chain Reaction - veterinary</subject><subject>Sex Determination Analysis - veterinary</subject><subject>sexing</subject><subject>Y Chromosome - chemistry</subject><issn>0042-4900</issn><issn>2042-7670</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkN1rFDEUxYModq0--qoDQvHBWW--dx5raVUoKNr6GjLZZMySmbTJzNb9780wC4IP-nTvhd8593AQeolhjTEV7_dpjblcY7nmmD5CKwKM1FJIeIxWMO-sAThBz3LeAZCGU_IUnWBBGCOUrdDX80GPsfdGh3fVT5_HGGI3X5UetlVnBzt6U_lhb_PoOz36OOQqukpX2f6adAiHAsZehzjlqot6fI6eOB2yfXGcp-j26vLm4lN9_eXj54vz67otj6EWDDYcnHPSEKkpB0O45CANZsCd4C0mDMRGSGu3EgtDqG4NlhvnGrLltqGn6GzxvUvxfirpVO-zsSHowZYsSmwkBc54Ad_8Be7ilIaSTWEpG8Jkw2a7eqFMijkn69Rd8r1OB4VBzUWrfVKl6KJRpejCvzq6Tm1vt3_oY7MFEAvw4IM9_NtN_bi8-fbhCoTAUISvF6HTUeku-axuvxPAFDAwoGIm3i5E2-_-E_M3oiyeAw</recordid><startdate>20051022</startdate><enddate>20051022</enddate><creator>Hafez, S. A.</creator><creator>Huckle, W. R.</creator><creator>Caceci, T.</creator><general>BMJ Publishing Group Limited</general><general>Blackwell Publishing Ltd</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20051022</creationdate><title>Anatomical, histological and genetic investigations of a sexually anomalous goat</title><author>Hafez, S. A. ; Huckle, W. R. ; Caceci, T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b4230-640850fff7c27a350c257507c1405f65b12406867eed716c23abc178ff92d5e93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Animals</topic><topic>Diagnosis, Differential</topic><topic>Disorders of Sex Development - diagnosis</topic><topic>Disorders of Sex Development - pathology</topic><topic>Disorders of Sex Development - veterinary</topic><topic>Female</topic><topic>genetic techniques and protocols</topic><topic>Goat Diseases - diagnosis</topic><topic>Goat Diseases - pathology</topic><topic>Goats</topic><topic>Polymerase Chain Reaction - veterinary</topic><topic>Sex Determination Analysis - veterinary</topic><topic>sexing</topic><topic>Y Chromosome - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hafez, S. A.</creatorcontrib><creatorcontrib>Huckle, W. R.</creatorcontrib><creatorcontrib>Caceci, T.</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Veterinary record</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hafez, S. A.</au><au>Huckle, W. R.</au><au>Caceci, T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anatomical, histological and genetic investigations of a sexually anomalous goat</atitle><jtitle>Veterinary record</jtitle><addtitle>Vet Rec</addtitle><date>2005-10-22</date><risdate>2005</risdate><volume>157</volume><issue>17</issue><spage>513</spage><epage>516</epage><pages>513-516</pages><issn>0042-4900</issn><eissn>2042-7670</eissn><abstract>An apparently female goat was masculine in appearance and had strong male-pattern libido and behaviour. The goat’s DNA was subjected to PCR analysis and its reproductive system was examined anatomically and histologically. The external genitalia consisted of an apparent vulva in the normal position and a grossly enlarged clitoris. Two masses could be palpated lying subcutaneously in the inguinal region; when they were removed they had the macroscopic appearance of hypoplastic testes, and histologically they had atrophic tubules and prominent interstitial tissues. To exclude sex chimaerism, X and Y chromosome-specific targets were amplified by PCR, using bone marrow and muscle DNA templates. The goat had some Y chromosomespecific sequences such as SRY and BRY.I but lacked others, such as BOV97M.</abstract><cop>England</cop><pub>BMJ Publishing Group Limited</pub><pmid>16244234</pmid><doi>10.1136/vr.157.17.513</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0042-4900 |
| ispartof | Veterinary record, 2005-10, Vol.157 (17), p.513-516 |
| issn | 0042-4900 2042-7670 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68730545 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Animals Diagnosis, Differential Disorders of Sex Development - diagnosis Disorders of Sex Development - pathology Disorders of Sex Development - veterinary Female genetic techniques and protocols Goat Diseases - diagnosis Goat Diseases - pathology Goats Polymerase Chain Reaction - veterinary Sex Determination Analysis - veterinary sexing Y Chromosome - chemistry |
| title | Anatomical, histological and genetic investigations of a sexually anomalous goat |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T18%3A04%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Anatomical,%20histological%20and%20genetic%20investigations%20of%20a%20sexually%20anomalous%20goat&rft.jtitle=Veterinary%20record&rft.au=Hafez,%20S.%20A.&rft.date=2005-10-22&rft.volume=157&rft.issue=17&rft.spage=513&rft.epage=516&rft.pages=513-516&rft.issn=0042-4900&rft.eissn=2042-7670&rft_id=info:doi/10.1136/vr.157.17.513&rft_dat=%3Cproquest_cross%3E4013630941%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1779247949&rft_id=info:pmid/16244234&rfr_iscdi=true |