DNA Damage Levels and Biochemical Repair Capacities Associated with XRCC1 Deficiency

Base excision repair (BER) is the major corrective pathway for most spontaneous, oxidative, and alkylation DNA base and sugar damage. X-ray cross-complementing 1 (XRCC1) has been suggested to function at nearly every step of this repair process, primarily through direct protein−protein interactions....

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