Lack of phenotype for LTP and fear conditioning learning in calpain 1 knock-out mice

We previously proposed the hypothesis that calpain activation played an important role in long-term potentiation (LTP) of synaptic transmission in hippocampus. Two forms of calpain are predominant in brain tissues, calpain 1 (μ-calpain), activated by micromolar calcium concentration and calpain 2 (m...

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Veröffentlicht in:	Neurobiology of learning and memory 2005-11, Vol.84 (3), p.222-227
Hauptverfasser:	Grammer, Michael, Kuchay, Shafi, Chishti, Athar, Baudry, Michel
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Animals Avoidance Learning - physiology Behavior, Animal - physiology Biological and medical sciences Calpain Calpain - genetics Calpain - physiology Calpain knock-out Conditioning (Psychology) - physiology Electrophysiology Electroshock Fear - physiology Fear conditioning Freezing Reaction, Cataleptic Fundamental and applied biological sciences. Psychology Hippocampus - cytology Hippocampus - physiology Learning Learning. Memory Long-Term Potentiation - genetics Long-Term Potentiation - physiology LTP Mice Mice, Inbred C57BL Mice, Knockout Phenotype Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Synapses - physiology Synaptic physiology
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