A humanized murine monoclonal antibody protects mice either before or after challenge with virulent Venezuelan equine encephalomyelitis virus

1 Arbovirus Diseases Branch, Division of Vector-Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, PO Box 2087, Fort Collins, CO 80522, USA 2 Alexion Antibody Technologies,...

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Veröffentlicht in:	Journal of general virology 2006-09, Vol.87 (9), p.2467-2476
Hauptverfasser:	Hunt, Ann R, Frederickson, Shana, Hinkel, Christopher, Bowdish, Katherine S, Roehrig, John T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal - genetics Antibodies, Monoclonal - therapeutic use Antibodies, Viral - administration & dosage Antibodies, Viral - genetics Antibodies, Viral - therapeutic use Base Sequence Biological and medical sciences Cloning, Molecular Encephalitis Virus, Venezuelan Equine - immunology Encephalitis Virus, Venezuelan Equine - pathogenicity Encephalomyelitis, Venezuelan Equine - immunology Encephalomyelitis, Venezuelan Equine - prevention & control Encephalomyelitis, Venezuelan Equine - therapy Fundamental and applied biological sciences. Psychology Genes, Immunoglobulin Humans Immunization, Passive Immunoglobulin G - administration & dosage Immunoglobulin G - genetics Immunoglobulin G - therapeutic use Mice Microbiology Miscellaneous Molecular Sequence Data Neutralization Tests Oligodeoxyribonucleotides - genetics Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Venezuelan equine encephalitis virus Virology
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