Genes Encoding Enzymes Responsible for Biosynthesis of L-Lyxose and Attachment of Eurekanate during Avilamycin Biosynthesis

The oligosaccharide antibiotic avilamycin A is composed of a polyketide-derived dichloroisoeverninic acid moiety attached to a heptasaccharide chain consisting of six hexoses and one unusual pentose moiety. We describe the generation of mutant strains of the avilamycin producer defective in differen...

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Veröffentlicht in:	Chemistry & biology 2005-10, Vol.12 (10), p.1137-1143
Hauptverfasser:	Hofmann, Carsten, Boll, Raija, Heitmann, Björn, Hauser, Gerd, Dürr, Clemens, Frerich, Anke, Weitnauer, Gabriele, Glaser, Steffen J., Bechthold, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinobacteria - enzymology Carbohydrate Sequence Carboxy-Lyases - biosynthesis Carboxy-Lyases - genetics Escherichia coli - enzymology Escherichia coli - genetics Glucose - metabolism Molecular Sequence Data Molecular Structure Oligosaccharides - analysis Oligosaccharides - biosynthesis Oligosaccharides - metabolism Pentoses - biosynthesis
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