Synthesis of Biaryls via Catalytic Decarboxylative Coupling

We present a safe and convenient cross-coupling strategy for the large-scale synthesis of biaryls, commercially important structures often found in biologically active molecules. In contrast to traditional cross-couplings, which require the prior preparation of organometallic reagents, we use a copp...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 2006-08, Vol.313 (5787), p.662-664
Hauptverfasser: Goossen, Lukas J, Deng, Guojun, Levy, Laura M
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Sprache:eng
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