Asymmetric synthesis of cyclopropanes and dihydrofurans based on phosphine oxide chemistry

The asymmetric synthesis of gamma-azido trans-cyclopropyl ketones is accomplished via a short, simple and efficient sequence. The cyclopropanation step is achieved by an intramolecular nucleophilic ring closure, with a diphenylphosphinate leaving group, to give trans-cyclopropane exclusively. beta-K...

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Veröffentlicht in:	Organic & biomolecular chemistry 2006-01, Vol.4 (16), p.3108-3112
Hauptverfasser:	Fox, David J, Parris, Sean, Pedersen, Daniel Sejer, Tyzack, Charles R, Warren, Stuart
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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