Calcium Influx through Channels Other than Voltage-Dependent Calcium Channels Is Critical to the Pituitary Adenylate Cyclase-Activating Polypeptide-Induced Increase in Excitability in Guinea Pig Cardiac Neurons

: Pituitary adenylate cyclase‐activating polypeptide (PACAP) effects on intracellular calcium ([Ca2+]i) and excitability have been studied in adult guinea pig intracardiac neurons. PACAP increased excitability, but did not elicit Ca2+ release from intracellular stores. Exposure to a Ca2+‐deficient...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2006-07, Vol.1070 (1), p.317-321
Hauptverfasser:	HARDWICK, JEAN C., TOMPKINS, JOHN D., LOCKNAR, SARAH A., MERRIAM, LAURA A., YOUNG, BETH A., PARSONS, RODNEY L.
Format:	Artikel
Sprache:	eng
Schlagworte:	action potential generation Animals Calcium (intracellular) Calcium - metabolism calcium influx Cytosol - drug effects Cytosol - metabolism Guinea Pigs Heart - drug effects intracellular calcium release Ion Channel Gating Ion Channels - metabolism Myocardium - metabolism Neurons - drug effects Neurons - metabolism PACAP Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology voltage-dependent calcium channels
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