Computational methods for the design of effective therapies against drug resistant HIV strains

The development of drug resistance is a major obstacle to successful treatment of HIV infection. The extraordinary replication dynamics of HIV facilitates its escape from selective pressure exerted by the human immune system and by combination drug therapy. We have developed several computational me...

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Veröffentlicht in:	Bioinformatics 2005-11, Vol.21 (21), p.3943-3950
Hauptverfasser:	Beerenwinkel, Niko, Sing, Tobias, Lengauer, Thomas, Rahnenführer, Jörg, Roomp, Kirsten, Savenkov, Igor, Fischer, Roman, Hoffmann, Daniel, Selbig, Joachim, Korn, Klaus, Walter, Hauke, Berg, Thomas, Braun, Patrick, Fätkenheuer, Gerd, Oette, Mark, Rockstroh, Jürgen, Kupfer, Bernd, Kaiser, Rolf, Däumer, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Database Management Systems Databases, Factual Drug Design Drug Information Services Drug Resistance, Viral - drug effects Drug Resistance, Viral - genetics Drug Therapy, Computer-Assisted - methods Fundamental and applied biological sciences. Psychology General aspects Genetic Therapy HIV Infections - drug therapy Human immunodeficiency virus Humans Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Viral Vaccines - administration & dosage Viral Vaccines - genetics
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