Mitotic Activation of the Kinase Aurora-A Requires Its Binding Partner Bora

The protein kinase Aurora-A is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis. Here, we describe the identification of Bora, a conserved protein that is required for the activation of Aurora-A at the onset of mitosis. In the Drosophila periph...

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Veröffentlicht in:Developmental cell 2006-08, Vol.11 (2), p.147-157
Hauptverfasser: Hutterer, Andrea, Berdnik, Daniela, Wirtz-Peitz, Frederik, Žigman, Mihaela, Schleiffer, Alexander, Knoblich, Juergen A.
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Sprache:eng
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