Synthesis and Assignment of Absolute Configuration of (−)-Oleocanthal:  A Potent, Naturally Occurring Non-steroidal Anti-inflammatory and Anti-oxidant Agent Derived from Extra Virgin Olive Oils

Effective total syntheses and the assignment of absolute configurations of both the (+)- and (−)-enantiomers of oleocanthal 1 (a.k.a. deacetoxy ligstroside aglycon), the latter derived from extra virgin olive oils and known to be responsible for the back of the throat irritant properties of olive oi...

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Veröffentlicht in:	Organic letters 2005-10, Vol.7 (22), p.5075-5078
Hauptverfasser:	Smith, Amos B, Han, Qiang, Breslin, Paul A. S, Beauchamp, Gary K
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehydes - chemical synthesis Aldehydes - chemistry Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis Anti-Inflammatory Agents, Non-Steroidal - chemistry Antioxidants - chemical synthesis Antioxidants - chemistry Molecular Structure Olive Oil Phenols - chemical synthesis Phenols - chemistry Plant Oils - chemistry Stereoisomerism
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