Evaluation of psychosomatic stress in children by measuring salivary chromogranin A
Aim: To investigate the usefulness of salivary chromogranin A (CgA) and cortisol as stress markers, and the effects of distraction on the suppression of stress in children. Methods: We examined salivary CgA and cortisol responses before and after venipuncture in hospitalized children with and withou...
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| Veröffentlicht in: | Acta Paediatrica 2006-08, Vol.95 (8), p.935-939 |
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| container_title | Acta Paediatrica |
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| creator | Lee, Tsubasa Shimizu, Toshiaki Iijima, Megumi Obinata, Kaoru Yamashiro, Yuichiro Nagasawa, Shingo |
| description | Aim: To investigate the usefulness of salivary chromogranin A (CgA) and cortisol as stress markers, and the effects of distraction on the suppression of stress in children. Methods: We examined salivary CgA and cortisol responses before and after venipuncture in hospitalized children with and without distraction using a kaleidoscope. Results: Salivary CgA levels immediately after venipuncture were significantly higher than those immediately before it, and at 60 min after venipuncture they were significantly lower than those immediately after it. However, salivary cortisol showed no significant differences at any of the three time points. In contrast, distracted by the kaleidoscope, there were no significant differences in salivary CgA and cortisol levels at all three time points.
Conclusion: In children, salivary CgA level is a useful marker of stress. As an index of the effect of distraction, the measurement of salivary CgA is useful. |
| doi_str_mv | 10.1080/08035250500538940 |
| format | Article |
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Conclusion: In children, salivary CgA level is a useful marker of stress. As an index of the effect of distraction, the measurement of salivary CgA is useful.</description><identifier>ISSN: 0803-5253</identifier><identifier>EISSN: 1651-2227</identifier><identifier>DOI: 10.1080/08035250500538940</identifier><identifier>PMID: 16882565</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Attention - physiology ; Biological and medical sciences ; Biomarkers - metabolism ; Case-Control Studies ; Child ; Chromogranin A ; Chromogranin A - metabolism ; cortisol ; Female ; General aspects ; Hospitalization ; Humans ; Hydrocortisone - metabolism ; Male ; Medical sciences ; Phlebotomy - psychology ; Psychophysiologic Disorders - etiology ; Psychophysiologic Disorders - metabolism ; psychosomatic stress ; saliva ; Saliva - metabolism ; stress marker ; Stress, Psychological - etiology ; Stress, Psychological - metabolism</subject><ispartof>Acta Paediatrica, 2006-08, Vol.95 (8), p.935-939</ispartof><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4795-322f0511d9360ce22e0d91d6e2501e1022dd46fd13367b3ede6b2290665695ee3</citedby><cites>FETCH-LOGICAL-c4795-322f0511d9360ce22e0d91d6e2501e1022dd46fd13367b3ede6b2290665695ee3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1080%2F08035250500538940$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1080%2F08035250500538940$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17997338$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16882565$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Tsubasa</creatorcontrib><creatorcontrib>Shimizu, Toshiaki</creatorcontrib><creatorcontrib>Iijima, Megumi</creatorcontrib><creatorcontrib>Obinata, Kaoru</creatorcontrib><creatorcontrib>Yamashiro, Yuichiro</creatorcontrib><creatorcontrib>Nagasawa, Shingo</creatorcontrib><title>Evaluation of psychosomatic stress in children by measuring salivary chromogranin A</title><title>Acta Paediatrica</title><addtitle>Acta Paediatr</addtitle><description>Aim: To investigate the usefulness of salivary chromogranin A (CgA) and cortisol as stress markers, and the effects of distraction on the suppression of stress in children. Methods: We examined salivary CgA and cortisol responses before and after venipuncture in hospitalized children with and without distraction using a kaleidoscope. Results: Salivary CgA levels immediately after venipuncture were significantly higher than those immediately before it, and at 60 min after venipuncture they were significantly lower than those immediately after it. However, salivary cortisol showed no significant differences at any of the three time points. In contrast, distracted by the kaleidoscope, there were no significant differences in salivary CgA and cortisol levels at all three time points.
Conclusion: In children, salivary CgA level is a useful marker of stress. As an index of the effect of distraction, the measurement of salivary CgA is useful.</description><subject>Adolescent</subject><subject>Attention - physiology</subject><subject>Biological and medical sciences</subject><subject>Biomarkers - metabolism</subject><subject>Case-Control Studies</subject><subject>Child</subject><subject>Chromogranin A</subject><subject>Chromogranin A - metabolism</subject><subject>cortisol</subject><subject>Female</subject><subject>General aspects</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Hydrocortisone - metabolism</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Phlebotomy - psychology</subject><subject>Psychophysiologic Disorders - etiology</subject><subject>Psychophysiologic Disorders - metabolism</subject><subject>psychosomatic stress</subject><subject>saliva</subject><subject>Saliva - metabolism</subject><subject>stress marker</subject><subject>Stress, Psychological - etiology</subject><subject>Stress, Psychological - metabolism</subject><issn>0803-5253</issn><issn>1651-2227</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE9PGzEQxS1UBCn0A3BBeym3Lf4T2-tjhIBWoikIUI-WY8-C29118GRp8-3rKFE59NDDyNLM773xPEJOGP3EaEPPSwnJJZWUStGYKd0jE6Ykqznn-h2ZbOZ1AcQheY_4g1IuzFQdkEOmmoZLJSfk_vLVdaNbxTRUqa2WuPbPCVNfOr7CVQbEKg6Vf45dyDBUi3XVg8Mxx-GpQtfFV5fXZZxTn56yGwo7Oyb7resQPuzeI_J4dflw8bm--Xb95WJ2U_upNrIWnLdUMhaMUNQD50CDYUFBuYgBo5yHMFVtYEIovRAQQC04N1QpqYwEEEfkbOu7zOllBFzZPqKHrnMDpBGtajSV2vACsi3oc0LM0Npljn35uGXUbpK0_yRZNKc783HRQ3hT7KIrwMcd4NC7ri3H-4hvnDZGC9EUTm65X7GD9f8329ntzIiNf73VRVzB7786l39apYWW9vv82vI5_3o3v9f2TvwBpRKYtA</recordid><startdate>200608</startdate><enddate>200608</enddate><creator>Lee, Tsubasa</creator><creator>Shimizu, Toshiaki</creator><creator>Iijima, Megumi</creator><creator>Obinata, Kaoru</creator><creator>Yamashiro, Yuichiro</creator><creator>Nagasawa, Shingo</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200608</creationdate><title>Evaluation of psychosomatic stress in children by measuring salivary chromogranin A</title><author>Lee, Tsubasa ; Shimizu, Toshiaki ; Iijima, Megumi ; Obinata, Kaoru ; Yamashiro, Yuichiro ; Nagasawa, Shingo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4795-322f0511d9360ce22e0d91d6e2501e1022dd46fd13367b3ede6b2290665695ee3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adolescent</topic><topic>Attention - physiology</topic><topic>Biological and medical sciences</topic><topic>Biomarkers - metabolism</topic><topic>Case-Control Studies</topic><topic>Child</topic><topic>Chromogranin A</topic><topic>Chromogranin A - metabolism</topic><topic>cortisol</topic><topic>Female</topic><topic>General aspects</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Hydrocortisone - metabolism</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Phlebotomy - psychology</topic><topic>Psychophysiologic Disorders - etiology</topic><topic>Psychophysiologic Disorders - metabolism</topic><topic>psychosomatic stress</topic><topic>saliva</topic><topic>Saliva - metabolism</topic><topic>stress marker</topic><topic>Stress, Psychological - etiology</topic><topic>Stress, Psychological - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Tsubasa</creatorcontrib><creatorcontrib>Shimizu, Toshiaki</creatorcontrib><creatorcontrib>Iijima, Megumi</creatorcontrib><creatorcontrib>Obinata, Kaoru</creatorcontrib><creatorcontrib>Yamashiro, Yuichiro</creatorcontrib><creatorcontrib>Nagasawa, Shingo</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta Paediatrica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Tsubasa</au><au>Shimizu, Toshiaki</au><au>Iijima, Megumi</au><au>Obinata, Kaoru</au><au>Yamashiro, Yuichiro</au><au>Nagasawa, Shingo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of psychosomatic stress in children by measuring salivary chromogranin A</atitle><jtitle>Acta Paediatrica</jtitle><addtitle>Acta Paediatr</addtitle><date>2006-08</date><risdate>2006</risdate><volume>95</volume><issue>8</issue><spage>935</spage><epage>939</epage><pages>935-939</pages><issn>0803-5253</issn><eissn>1651-2227</eissn><abstract>Aim: To investigate the usefulness of salivary chromogranin A (CgA) and cortisol as stress markers, and the effects of distraction on the suppression of stress in children. Methods: We examined salivary CgA and cortisol responses before and after venipuncture in hospitalized children with and without distraction using a kaleidoscope. Results: Salivary CgA levels immediately after venipuncture were significantly higher than those immediately before it, and at 60 min after venipuncture they were significantly lower than those immediately after it. However, salivary cortisol showed no significant differences at any of the three time points. In contrast, distracted by the kaleidoscope, there were no significant differences in salivary CgA and cortisol levels at all three time points.
Conclusion: In children, salivary CgA level is a useful marker of stress. As an index of the effect of distraction, the measurement of salivary CgA is useful.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>16882565</pmid><doi>10.1080/08035250500538940</doi><tpages>5</tpages></addata></record> |
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| subjects | Adolescent Attention - physiology Biological and medical sciences Biomarkers - metabolism Case-Control Studies Child Chromogranin A Chromogranin A - metabolism cortisol Female General aspects Hospitalization Humans Hydrocortisone - metabolism Male Medical sciences Phlebotomy - psychology Psychophysiologic Disorders - etiology Psychophysiologic Disorders - metabolism psychosomatic stress saliva Saliva - metabolism stress marker Stress, Psychological - etiology Stress, Psychological - metabolism |
| title | Evaluation of psychosomatic stress in children by measuring salivary chromogranin A |
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